Matrine treatment of chronic hepatitis B Efficacy of liver fibrosis.doc

 PAGE \* MERGEFORMAT 8 Matrine treatment of chronic hepatitis B Efficacy of liver fibrosis Of: Wei Zhao Yong, Su Fengchun, Qin Junde [Abstract] Objective To observe Oxymatrine liver fibrosis in chronic hepatitis B patients. Methods 57 patients were randomly divided into two groups selected, the treatment group, 30 cases of intramuscular interferon @ 2a 300U / day, once every 20 days changed every other day after a course of 6 months, were added oxymatrine 0.6 / day, continuous intravenous infusion of 2 months, later changed to oral administration of soft capsules kurorinone 0.2 g, 3 times a day for 4 months . the control group of 27 patients, only intramuscular interferon @ 2a 300 U / day, once every 20 days to change every other day, for 6 months. Results After treatment, decreased serum hepatic fibrosis, but the efficacy of the treatment group was significantly than the control group (P lt;0.05 or 0.01. Conclusion Oxymatrine the treatment of chronic hepatitis B liver fibrosis have significant effect. [Keywords:] chronic hepatitis B, liver fibrosis, matrine, interferon @ 2a There is no specific treatment of chronic hepatitis B, the current comprehensive treatment measures, including anti-virus, immune regulation, improve liver function and liver fibrosis treatment, clinical often anti-virus therapy in the treatment of liver Liver measures, ignore the anti-liver fibrosis treatment. We use Oxymatrine oxymatrine and soft capsules in patients with liver fibrosis in chronic hepatitis B, and achieved good results, are reported below. Materials and Methods 1. Cases, 57 cases were selected to choose our hospital in patients with liver fibrosis in chronic hepatitis B, diagnosis revised in 2000 lt;lt;Viral Hepatitis Prevention Programmegt;gt; [1], and in accordance with the following conditions: serum liver markedly abnormal fibrosis, hyaluronic acid (HA, laminin (LN, IV collagen (IV C, the former type collagen peptide (P P and other four indicator