Medicine arsenic (arsenic trioxide) Advances in studies on anti-hepatoma.docVIP

 PAGE \* MERGEFORMAT 15 Medicine arsenic (arsenic trioxide) Advances in studies on anti-hepatoma Abstract Experimental and clinical studies have demonstrated that traditional Chinese medicine arsenic trioxide (As2O3) can effectively treat acute promyelocytic leukemia, the As2O3 anti-solid tumor studies have become the research hotspot of anti-tumor and anti-liver cancer research increasing number of reports in this article refer to domestic and international literature on anti-hepatoma effect of As2O3 experimental study and clinical application of advances reviewed. Keywords: anti-hepatoma effect of arsenic trioxide apoptosis in liver cancer Advances in Antihepato Eellular Carcinoma of Arsenic Trioxide Abstract: Clinical trials have demonstrated that arsenic trioxide is effective in the treatment of acute promyelocytic leukemia. Based on this fact, more and more studies have been carried out to study its role in the treatment of human hepatocarcinoma cells. Thus we review overseas and domestic literature and summarize treatment of hepatocellular carcinoma with arsenic trioxide for experiments and clinical study. Keywords:: Arsenic trioxide; Hepatocarcinoma; Antihepatocellular carcinoma; Cellular apoptosis Earliest human chemotherapy for the treatment of malignant tumors may be arsenic (arsenic trioxide As2O3), arsenic trioxide is the arsenic of traditional Chinese medicine the main active ingredient, has long been considered to be toxic and carcinogenic, but as a medicine has been around 2000 400 years of history, as the anti-tumor in our country there are at least a century of history [1]. Recent studies have found that, As2O3 on acute promyelocytic leukemia (APL) can induce apoptosis, further confirmed that arsenic could inhibit gastric cancer, lung cancer, prostate cancer, liver cancer and other solid tumors, tumor cell growth, suggesting that arsenic trioxide is a broad-spectrum antitumor agents [2]. Since the di