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Narrow-band UVB treatment of senile skin pruritus simple observation
PAGE \* MERGEFORMAT 7
Narrow-band UVB treatment of senile skin pruritus simple observation
Of: at the Yan Fu Aihua Zheng Hua Liu Bing
[Keywords:] narrow-band UVB, pruritus, senile
Simple treatment of senile pruritus tricky, simple antihistamine is ineffective. Author based on narrow-band 311 nm UV wave mechanism and biological effects jointly, loratadine and topical calamine lotion simple senile 30 cases of skin itching.
1 Materials and Methods
1.1 Clinical data
60 senile pruritus from hospital dermatology clinic patients, 36 males and 24 females, aged 60 to 82 years, mean 67.7 years, duration of 1 to 5 years, an average of 3.5 years. Randomly divided into two groups and control group 30 patients. the two groups in age, gender, disease duration and severity were not statistically different, comparable.
1.2 The inclusion criteria
1 w in treatment of other antihistamines and not taking medicine, 1 month ago had not served corticosteroids, immunosuppressive agents, non-system disease, and primary skin diseases, no UV allergies.
1.2 Treatment
Study group using narrow spectrum UVB (Waldmann, Germany company, UV1000L type UVB311 nm treatment for total body irradiation treatment. Based on skin type, the first dose of 0.6 ~ 0.8 J/cm2, 3 times / w, irradiated the next day, each dose in the absence of increase in response to the case of erythema 0.2 J/cm2, while oral administration to loratadine 10 mg, 1 times / d, topical calamine lotion, 2 times / d. control group was treated to loratadine 10 mg, 1 times / d, topical calamine lotion, 2 / d.4 w as a course of treatment.
1.3 determine the efficacy of standard
Healing: itching disappeared, markedly: significantly reduced itching, effective: to reduce itching, skin occasional scratch, is not valid: there is still much itching or no change. Cure plus markedly effective rate to calculate.
1.4 Statistical Methods
Statistical software used SPSS15 2 test.
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