Of drugs to improve cerebral ischemic tolerance.docVIP

 PAGE \* MERGEFORMAT 12 Of drugs to improve cerebral ischemic tolerance [Abstract] Objective of drugs to improve cerebral ischemic tolerance are discussed. Analyze the characteristics of the high ischemic tolerance and mechanisms of chemical drugs, traditional Chinese medicine to improve the characteristics of ischemic tolerance and the possible mechanism is proposed to carry out traditional Chinese medicine to improve ischemic tolerance of ideas. analysis of the results of chemical substances to improve the characteristics of ischemic tolerance and the possible mechanisms proposed on the basis of the Chinese characteristics of ischemic tolerance and the possible mechanisms. conclusions of traditional Chinese medicine to improve the brain to carry out ischemic tolerance in more prospects, improve the microcirculation is the major mechanism of ischemic tolerance. [Keywords:] Cerebral ischemia; chemical drugs; medicine Ischemic tolerance phenomenon [1] (Brain ischemic tolerance, BIT) is the pre-transient ischemia or hypoxia stimulate or mobilize the body mild inherent protection, so that the body of the subsequent severe ischemia, hypoxia produced defense and protection of the phenomenon. ischemic tolerance phenomenon was originally found in the study of myocardial ischemia, brain, skeletal muscle, liver, kidney, small intestine and other organs found a similar phenomenon. 1, the mechanism of ischemic tolerance The generation of ischemic tolerance involves neurotransmitters, receptors, channels, gene expression, protein synthesis and more complex aspects of biological process regulation. Most people think that the general mechanism BIT: Ischemic preconditioning can cause tissue to adenosine release based endogenous neurotransmitters, and with the corresponding receptors, signal transduction pathways by activating specific genes start to express the effect of protective material. is that the mechanism of ischemic tolerance are excitatory amino acids