On Red Mau Tso chemical constituents and pharmacological research progress in.docVIP

 PAGE \* MERGEFORMAT 14 On Red Mau Tso chemical constituents and pharmacological research progress in Authors: Qiang Zhao Hua Yang Lee Valley to build a gull Paper Keywords: red Mau Tso; chemical composition; pharmacological effects Abstract: Red Mau Tso alkaloids main chemical constituents for a variety of isoquinoline alkaloids, their alkaloid with antibacterial, antimicrobial, anti-hemolysis and improvement of microcirculation, and smooth muscle of the central inhibitory, role in improving immunity, etc. , on myocardial cells and liver injury in mice also have protective effects. Red Mau Tso’s medicinal value and has broad prospects for the development and application. A red Mau Tso chemical and toxic components Red Mau Tso main chemical components for a variety of isoquinoline alkaloids. Full grass containing: isocorydine alkali, protopine [3,4], Corydalis alkali, isocorydine brown base, wooden Lan base, sanguinarine, do not base hidden items, sea papaverine. Root with: protopine, chelerythrine base, sanguinarine, do not base hidden items, hidden items alkali [2,5]. All grass species in the top 5 Red Mau Tso’s main active ingredient, have been isolated crystal, of which the first three kinds of crystals have been an effective separation, purification and identification of [6]. Isocorydine base after intraperitoneal injection in mice appear hyperactive behavior, the larger dose occurs salivation, vomiting, drowsiness, convulsions, stiffness and other states as well. Mice by intraperitoneal injection of the LD50 for the 52mg/kg, intravenous injection of the LD50 of 49mg/kg. Isocorydine alkali rats were given intramuscular injection 4mg, 10mg and 24mg/kg, day 1, continuous 30d. Rats, appearance, activity, diet and normal growth and development; hemogram, GPT, and NPN Dengjun within normal limits; pathologic examination, heart, lung, kidney, adrenal gland, liver, brain Dengjun no obvious abnormalities [7,8] . 2 Red Mau Tso Determination of the activ