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On the central nervous system brain natriuretic peptide in Progress
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On the central nervous system brain natriuretic peptide in Progress
Paper Keywords: central nervous system; brain natriuretic peptide; head trauma
Abstract: It is now found by the Department of natriuretic peptide atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP) and three types of receptors composed of three endogenous ligand system. They are widely distributed within the central nervous system. Study of brain natriuretic peptide (BNP) in the central nervous system (CNS) Biochemical characteristics and distribution, the release of the law shows that brain natriuretic peptide (BNP) on the water-salt metabolism in the central regulatory role, in order to clarify the traumatic brain injury (ACI) When the incidence of water-electrolyte imbalance mechanism has important implications for the clinical prognosis and treatment of ACI guidance.
Brain natriuretic peptide (brain natriuretic peptide.BNP) is the second atrial natriuretic peptide (atrial natriuretic peptide, ANP) natriuretic peptide after the discovery of another member of the family in 1988 by the Japanese scholar Matsuo, Sudoh, etc. from porcine brain separation, passivation out, after the myocardial cells can also be found in synthesis and secretion of BNP. With the ANP, like, BNP has a powerful natriuretic, diuretic, diastolic blood vessels and inhibit the renin - aldosterone system and other role, but in gene expression, synthesis and secretion of parts, metabolic clearance and in the central nervous system (central nervous systerm, CNS) in the The distribution and so different from the ANP. With the radioimmunoassay, immunohistochemistry, molecular biology, the BNP’s basic research and its role in the central nervous system gradually by people concerned about the reports in this regard are reported as follows.
1 BNP biochemical characteristics of
BNP is a kind of bioactive peptides from 26 amino acids, BNP-26 is its basi
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