Paclitaxel combined with cisplatin for treatment of advanced 3-negative breast cancer 18 cases of Effect.docVIP

 PAGE \* MERGEFORMAT 3 Paclitaxel combined with cisplatin for treatment of advanced 3-negative breast cancer 18 cases of Effect Author: Zheng Xiuping Cao Yongfeng Zhu Ji Qian Yong Shun-Min Ding [Abstract] Objective: To observe and evaluation of paclitaxel and cisplatin in advanced 3-negative breast cancer, the efficacy and safety. Methods: 18 cases with pathology and imaging diagnosis of advanced breast cancer, and immunohistochemical staining of estrogen receptor, progesterone receptor, human epidermal growth factor receptor-negative patients were given paclitaxel, cisplatin treatment 2 cycle, evaluate the efficacy and toxicity. Results: Paclitaxel combined with cisplatin in the treatment of advanced 3-negative breast cancer, 12 cases (61.1%), the main toxicity was myelosuppression and gastrointestinal reactions. Conclusions: Paclitaxel combined with cisplatin for advanced 3-negative breast cancer is accurate, and well tolerated and worthy to be popularized. [Keywords:] breast cancer; paclitaxel; cis-platinum; chemical treatment Breast cancer is the most common malignancy among women, and seriously endanger the health of women. According to the statistics [1], the world each year about 120 million new cases, especially in a few developed countries, breast cancer incidence has been ranked the top women’s cancer, my breast cancer incidence Yicheng an upward trend year after year. In recent years, due to surgery, radiotherapy, chemotherapy, endocrine and molecular targeted therapy such as the rapid development of a comprehensive treatment measures, breast cancer survival rate and median survival has been significantly improved. But there are still some patients with recurrence and metastasis, in particular the estrogen receptor, progesterone receptor, human epidermal growth factor receptor-3-negative patients with breast cancer treatment became difficult. MDT is the preferred treatment of such patients, our hospital in January 2007 ~ August 2008 of 18 patient