Prognosis of coma Multivariate Analysis.doc

 PAGE \* MERGEFORMAT 14 Prognosis of coma Multivariate Analysis [Keywords:] coma patients; prognosis; demographic; clinical indicators; physiological and biochemical factors; imaging As medical technology, especially the intensive care medical technology advances, more and more patients survive severe brain injury. Now, we are more concerned about the prognosis of these patients and quality of life .40 years ago, Plum and Posner [1] for the first time proposed diagnostic criteria for coma and stupor. Since then, many scholars working in acute brain injury and coma in clinical research. For a long time, clinical indicators to assess local or diffuse brain injury in comatose patients only partial indicators of brain function [2 ] .1975 years, Jennett and Bond [3] proposed six months to one year after injury, the recovery of the patient’s Glasgow Outcome Classification (Glasgow Outcome Scale, GOS), 1 point: death; 2 points: the survival of plants, long-term coma, was to cortex or to brain tonic state; 3: severe disability, need to take care of others; 4: moderate disability, life can take care of themselves; 5: well, adults can work and study. In recent years, many scholars at home and abroad, including clinical factors, including indicators to predict GOS scores of patients with coma and guidance of clinical treatment of coma patients. but, most scholars in patients with traumatic coma prognostic factors, and not entirely clear what factors affect the prognosis of comatose patients as well as the correlation between the independent factors. access to relevant literature on the factors that affect the prognosis of comatose patients can be divided into demographic, clinical, physiological and biochemical factors and imaging of four parts. 1 Demographics Major demographic including age, gender, educational level, cause and so on. According to an international multicenter study confirmed that age in developed countries, the most important factor predictin