Prozac treatment on the efficacy of post-stroke depression.docVIP

 PAGE \* MERGEFORMAT 6 Prozac treatment on the efficacy of post-stroke depression [Abstract] Objective: To investigate the fluoxetine in treatment of post-stroke depression. Methods: 94 cases of patients with depression into treatment group (48 cases) and control group (46 cases) and cerebrovascular disease with conventional drug therapy , in which the treatment group plus fluoxetine in treatment. Hamilton (HAMD) score and evaluated neurologic impairment and rehabilitation. Results: After treatment, the HAMD scale reduced rate compared with the control group, the difference highly significant (P lt;0.01), neurological impairment score lower value in the treatment group was significantly higher (P lt;0.01). Conclusion: Prozac can improve the efficacy of post-stroke depression and improve neurological function in patients. [Keywords:] stroke; depression; Prozac Post-stroke depression (Post Stroke Depression, PSD), is the most common complication of stroke, accounting for 25% of patients with stroke to 79% [1], the symptoms of stroke usually after 6 months to 2 years, the most serious, not only affects the patient’s quality of life, will hinder the recovery of nerve function. Prozac is a non-selective 5-HT (5 NH) reuptake inhibitors, the active ingredient fluoxetine hydrochloride, clinical the application can improve depression in patients to promote recovery of neurological function. This study of 48 patients treated with Prozac in the efficacy of patients with depression were observed to investigate the clinical value of Prozac. 1 Materials and methods 1.1 General Information Study for the hospital in September 2003 ~ August 2008 to stay the Court’s Department of Neurology, 94 cases of stroke in depressed patients, selection criteria were: ① the country of 1995 4th meeting standards set by cerebrovascular disease, and are The diagnosis of brain CT or MRI; ② all stroke patients, including cerebral hemorrhage and cerebral infarction; ③ Hamilton (