Robertsonian translocation less severe Asthenospermia 1 case of a successful ICSI progesterone.docVIP

 PAGE \* MERGEFORMAT 7 Robertsonian translocation less severe Asthenospermia 1 case of a successful ICSI progesterone Of: Zhaojun Li, Huo Zhenghao, Hu Rong, Xu Xian Li Fenghua [Keywords:] Robertsonian translocation less severe progesterone asthenospermia ICSI Robertsonian translocation (Robertsonian translocation) is a common infertility chromosome structural abnormalities, because of its major genes are not lost, carriers and more normal phenotype, but often repeated history of adverse pregnancy spontaneous abortion [1-5 ], male carriers also usually presents obstacles to spermatogenesis leading to infertility [1-3]. intracytoplasmic sperm injection follicle (ICSI) is the treatment of severe Asthenospermia less effective means, for pre-implantation genetic diagnosis The premise of technology [1], now in our region and the first male Robertsonian translocation associated with spermatogenic dysfunction in patients with severe oligospermia Asthenospermia get pregnant through ICSI Technical case report follows. 1 Case information Patients 27 years old, married 5 years to conceive a child of farmers, many semen less severe for the very weak sperm; endocrine normal, LH: 7.2mIU L-1, FSH: 4.1mIU L-1, E2: 8pmol L-1, PRL: 12ng L-1, T: 303.9ng dL-1, ultrasonography showed bilateral testicular gonads, epididymis, seminal vesicles the size of normal, bilateral varicocele; chromosome examination revealed 45, XY, rob (13; 14) (q10; q10), for the Robertsonian translocation carriers; to HMG, HCG, Chinese medicine treatment of semen improvement was not obvious, is still less severe weak sperm, the woman 27 years of age, menstrual regularity, endocrine normal, tubal angiography were bilateral tubal tortuosity on the move, the end of swelling, limited contrast agents gathered in the uterine horn above the normal chromosomes. The woman in the natural cycle luteal phase long protocol (1.25mg Dafei Lin) started ovulation, menstruation 3 days Gn (U-FSH, Li Shen