Sjogrens syndrome children the etiology and pathogenesis of.docVIP

 PAGE \* MERGEFORMAT 22 Sjogren’s syndrome children the etiology and pathogenesis of [Abstract] Sjogren’s syndrome (sj  gren syndrome, SS is a chronic inflammatory autoimmune disease, lesions are mainly lymphocytes and plasma cells and the size of the lacrimal and salivary glands exocrine glands, resulting in destruction of the gland, causing glandular characterized by decreased secretion of the body, resulting in a variety of clinical manifestations, but dry eyes and dry mouth as the main symptoms. Sjogren’s syndrome is accompanied by other diseases and is divided into two kinds of secondary and primary. as children of the original Development of Sjogren’s syndrome are rare, and secondary Sjogren’s syndrome is relatively common, but are difficult to diagnosis, clinical manifestations and adults are not identical. Moreover, the current etiology and pathogenesis of the disease is not entirely clear However, the preliminary view that: infection, environment, genes and the participation of the immune system and have a close relationship between the disease. In this paper, the cause of Sjogren’s syndrome children, and we reviewed the pathogenesis. [Keywords:] Sjogren’s syndrome, children, etiology, pathogenesis Sjogren’s syndrome (sj  gren syndrome, SS is a diffuse autoimmune disease, mainly affects exocrine glands, usually presents due to impaired salivary and lacrimal glands resulting from persistent dry mouth and dry eye disease patients [1]. The disease is accompanied by other diseases and is divided into two kinds of secondary and primary. The about 90% of patients were women, most age 30 to 50 years old, but can be seen at any age, including children, young people and so on. Zhangnai Zheng et al [2] Statistics of 186 cases of patients in Beijing from 1 to 0.9% in patients 10 years of age, 10 to 20 years old accounted for 2.6%, from 20 to 30 years old accounted for 9.5%. children with primary Sjogren’s syndrome are rare during , its severity and ext