The progress of bone tissue engineering.docVIP

 PAGE \* MERGEFORMAT 17 The progress of bone tissue engineering Keywords: Bone Tissue Engineering Progress The human body due to illness (poisoning, infection and congenital malformations), and trauma, cancer and other reasons caused by the tissues and organs of the defect and loss of function and can be transplanted to repair a variety of alternatives. Alternatives including autologous tissue, allogeneic organizations, heterogeneous organizations and synthetic materials. Although these alternatives have been used in clinical treatment, but inevitably there are problems and limitations, which force the plastic surgery and related disciplines workers for more appropriate and effective alternatives. The past two decades, due to the popularity of the organization type of culture techniques, cell biology, molecular biology, biochemistry and other disciplines to develop and biomedical materials development and utilization, resulting in a new discipline - tissue engineering (Tissue enigeering). An overview of tissue engineering Tissue engineering is the application of the principles of biology and engineering, research and development to repair, maintain and improve the function of damaged tissue of biological substitutes a discipline [1]. The basic method is the high concentration of in vitro function of living tissue related to cell proliferation, and planted in a biological good performance, biodegradable (or bio-resorbable) natural and artificial synthesis of extracellular matrix (Extracelluar matrix. ECM) on the. Together they then transplanted to the desired location, in the body cells continued to proliferate, while the scaffold structure is gradually being degraded, absorbed, and the result of the formation of new functional tissues and organs, but to repair the structure and restore function of the purpose of [1 ~ 5 ]. Currently, tissue engineering include the following studies: ① ECM development; ② biological properties of seed cells; ③ tissue engine