Vitamin A and the relationship between lower respiratory tract infection in Progress.docVIP

 PAGE \* MERGEFORMAT 15 Vitamin A and the relationship between lower respiratory tract infection in Progress [Keywords:] Vitamin A Study of lower respiratory tract infection in Progress A lack of vitamin (Vitamin A Deficiency, VAD) of the criterion of [2]: serum vitamin A concentration of 1.05 ~ 2.07 μ mol / L for normal, 0.70 ~ 1.05 μ mol / L for the lack of sub-clinical suspect, lower than 0.70 μ mol / L for the sub-clinical lack of, of which 0.50 ~ 0.70 μ mol / L for mild lack of, 0.35 ~ 0.50 μ mol / L for moderate lack of less than 0.35 μ mol / L is severely lacking. VAD incidence rate according to different countries and different regions, of which Africa, South Asia and Southeast Asia as the highest in West Africa there are about more than 100 million children with VAD, VAD children in Indonesia up to 58%. My survey results show that, VAD was 0.15%, sub-clinical VAD was 11.7%, suspicious VAD was 39.2% [3]. Acute lower respiratory tract infection (Acute Lower Respiratory Tract Infections, ALR TIs) is an issue affecting children’s health, global issues. Survey [4], ALR TIs mortality in both developed and developing countries have significant differences, the developed countries pneumonia in children under 5 years of age mortality rate is only 1% ~ 3%, while the developing countries is as high as 10% of ~ 25%. The study found, VAD in children with normal children ALR TIs The main difference is that the prevalence increased significantly. VA is now on the relationship with the lower respiratory tract infection research is summarized below. 1 VA and lung development VA affect lung differentiation and maturation: (1) morphological, VAD can lead to the trachea and bronchial squamous metaplasia, VA can be reversed to add this metaplasia; (2) VA affecting gene expression in the lung, Haq et al [5 ] The study found that lung tissue exists in retinoic acid nuclear receptors (RARs), in alveolar epithelial cells and fibroblasts are the expression of these recepto