Anisotropic WM conductivity reconstruction based on diffusion tensor magnetic resonance imaging a simulation study英文文献资料.docVIP

J. Biomedical Science and Engineering, 2010, 3, 776-784 JBiSE doi:10.4236/jbise.2010.38103 Published Online August 2010 (http://www.SciRP.org/journal/jbise/). Anisotropic WM conductivity reconstruction based on diffusion tensor magnetic resonance imaging: a simulation study* Dandan Yan , Wenlong Xu , Jing Li 1 1 2 1 2 College of Information Engineering, China JiLiang University, Hangzhou, China; Center for THz Research, China Jiliang University, Hangzhou, China. Email: dandanyan@ Received 18 May 2010; revised 8 June 2010; accepted 11 June 2010. ABSTRACT head tissues. In the electroencephalography (EEG) or magnetoencephalography (MEG) based source localiza- tion or imaging, the conductivity distribution is often assumed to be isotropic and piece-wise homogeneous. However, this assumption is not entirely accurate since the conductivity is highly anisotropic within the WM [1]. The more accurate conductivity distribution of the WM volume is needed for accurate source localization from EEG/MEG. The cerebral WM is considered as glia and axons bathing in the interstitial fluid. WM shows obvious ani- sotropy due to its much complicated nerve fiber distribu- tion. Some methods have been reported to get the ani- sotropic WM conductivity [2,3], which are based on Basser’s [4] theory to infer the electrical conductivity tensor from the water self-diffusion tensor measured by diffusion tensor magnetic resonance imaging (DT-MRI). Self-consistent differential effective medium approach (EMA) [2,5] was used to deduce the anisotropic conduc- The present study aims to estimate the in vivo anisot- ropic conductivities of the White Matter (WM) tis- sues by means of Magnetic Resonance Electrical Im- pedance Tomography (MREIT) technique. The real- istic anisotropic volume conductor model with dif- ferent conductivity properties (scalp, skull, C