Anti-diabetic effects of cold and hot extracted virgin coconut oil英文文献资料.docVIP

Vol.1, No.4, 118-123 (2011) Journal of Diabetes Mellitus doi:10.4236/jdm.2011.14016 Anti-diabetic effects of cold and hot extracted virgin coconut oil Mahadevappa Siddalingaswamy , Arunchand Rayaorth , Farhath Khanum 1* 2 1 1 * 2 Biochemistry Nutrition Discipline, Defense Food Research Laboratory, Mysore, India; Corresponding Author: mslswamy@ Department of Medical Biochemistry, Kannur University, Kannur, Kerala, India. Received 15 July 2011; revised 24 August 2011; accepted 5 September 2011. ABSTRACT causes of diabetes are consider to be, imbalanced food habits, change in life style, obesity, lack of physical acti- vity, uncontrolled oxidative stress, genetic defects etc. Coconut oil is one of the primary sources of energy, in tropical countries like costal India, Srilanka, Philippines, and Indonesia [1]. The oil holds high place of respect in ayurvedic medicine in India. Virgin coconut oil (VCO) a preparation of coconut oil without harsh processing such as refining, hydrogenation, deodorization, bleaching etc may retain native bioactive compounds present in it [2]. VCO extracted in cold and hot conditions shown to be rich in polyphenols. Lauric acid, present in coconut oil has been shown to possess insulino tropic properties in isolated perfused mouse islet model but not proven in diabetic animals [3]. It has been shown that hot extracted virgin coconut oil (HEVCO) possess better antioxidant potency than cold extracted virgin coconut oil (CEVCO) [4,5]. These two oils have been shown to inhibit lipo- protein oxidation with hypolipidemic effects [6]. In dia- betic patients antioxidants may play a vital role in im- proving insulin response to the loaded glucose and may reduce insulin resistance [7]. However information re- garding the anti-diabetic effects of CEVCO and HEVCO with their insul