Anti-inflammatory actions of acupuncture英文文献资料.docVIP

Review MediatorsofInflammation,12(2),59á / 69(April2003) ACUPUNCTURE has a beneficial effect when treating Anti-in?ammatoryactionsof manydiseasesandpainfulconditions,andtherefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel dis- ease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustainedeffectofacupuncturearemissing.Mechan- isms underlying the ascribed immunosuppressive actionsofacupuncture are reviewedin this commu- nication.Theacupuncture-controlledreleaseofneu- acupuncture Freek J. Zijlstra1,CA,Ineke vandenBerg-deLange1,2 Frank J. P. M. Huygen1andJan Klein1 , 1DepartmentofAnesthesiologyand 2Departmentof Epidemiology,ErasmusMedicalCentre,Centre location,P.O.Box2040,3000CARotterdam,The Netherlands ropeptides from nerve endings and subsequent vasodilative and anti-inflammatory effects through calcitoninegene-relatedpeptideishypothesised.The complexinteractionswithsubstanceP,theanalgesic contributionofb-endorphinandthebalancebetween cell-specificpro-inflammatoryandanti-inflammatory cytokines tumour necrosis factor-a and interleukin- 10arediscussed. CACorrespondingAuthor Tel:/31104635606 Fax / 31104637222 E-mail:f.zijlstra@erasmusmc.nl Key words: Acupuncture, In?ammation, Neuropeptides, Cytokines,Nitricoxide Introduction only with a clear-cut diagnosis, but also takes into account the complex pattern of disease-related factors.Theexactpatternanddegreeofdisharmony is unique for each individual. Therefore, the practi- tioneroftraditionalacupuncturewillapproacheach InChina,acupuncturehasbeenusedinthetreatment ofseveraldiseasesforatleast5200years.InEurope andtheUSA,thisintegralpartoftraditionalChinese medicine has become a visible component of the patientwit