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Antibacterial Properties of Silver-Loaded Plasma Polymer Coatings英文文献资料
HindawiPublishingCorporation
JournalofNanomaterials
Volume2012,ArticleID674145,9pages
doi:10.1155/2012/674145
ResearchArticle
AntibacterialPropertiesofSilver-Loaded
PlasmaPolymerCoatings
LydiePloux, MihaelaMateescu, KarineAnselme, andKrasimirVasilev
1 1 1 2
1
2
InstitutdeSciencedesMat′eriauxdeMulhouse,CNRSLRC7228,15rueJeanStarcky,BP2488,68057MulhouseCedex,France
MawsonInstituteandSchoolofAdvancedManufacturing,UniversityofSouthAustralia,MawsonLakesCampus,
MawsonLakes,SA5099,Australia
CorrespondenceshouldbeaddressedtoLydiePloux,lydie.ploux@uha.fr
Received8February2012;Accepted22March2012
AcademicEditor:HaifengChen
Copyright?2012LydiePlouxetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense,
whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited.
Inapreviouspaper,weproposednewsilvernanoparticles(SNPs)basedantibacterialcoatingsabletoprotecteukaryoticcellsfrom
SNPsrelatedtoxice?ects,whilepreservingantibacteriale?ciency.ASNPscontainingn-heptylamine(HA)polymermatrixwas
depositedbyplasmapolymerizationandcoatedbyasecondHAlayer.Inthispaper,weelucidatetheantibacterialactionofthese
newcoatings.WedemonstratedthatSNPs-loadedmaterialcanbecoveredbythinHApolymerlayerwithoutlosingtheantibac-
terialactivitytoplanktonicbacterialivinginthenearsurroundingsofthematerial.SNPs-containingmaterialsalsorevealedanti-
bacteriale?ectonadheredbacteria.Adheredbacterianumberwassigni?cantlyreducedcomparedtopureHAplasmapolymer
andthephysiologyofthebacteriawasa?ected.ThenumberofadheredbacteriadirectlydecreasedwiththicknessofthesecondHA
layer.Surprisingly,thequantityofcultivablebacteriaharvestedbytransfertonutritiveagardecreasednotonlywiththepresence
ofSNPs,butalsoinrelationtothecoveringHAlayerthickness,thatis,oppositelytotheincreaseinadheredbacterianumber.Two
hypothesesareproposedforthissurprisingresult(strongerattachmentorweakervitality),whichraisesthequestiono
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