Antibacterial Properties of Silver-Loaded Plasma Polymer Coatings英文文献资料.docVIP

Antibacterial Properties of Silver-Loaded Plasma Polymer Coatings英文文献资料.doc

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Antibacterial Properties of Silver-Loaded Plasma Polymer Coatings英文文献资料

HindawiPublishingCorporation JournalofNanomaterials Volume2012,ArticleID674145,9pages doi:10.1155/2012/674145 ResearchArticle AntibacterialPropertiesofSilver-Loaded PlasmaPolymerCoatings LydiePloux, MihaelaMateescu, KarineAnselme, andKrasimirVasilev 1 1 1 2 1 2 InstitutdeSciencedesMat′eriauxdeMulhouse,CNRSLRC7228,15rueJeanStarcky,BP2488,68057MulhouseCedex,France MawsonInstituteandSchoolofAdvancedManufacturing,UniversityofSouthAustralia,MawsonLakesCampus, MawsonLakes,SA5099,Australia CorrespondenceshouldbeaddressedtoLydiePloux,lydie.ploux@uha.fr Received8February2012;Accepted22March2012 AcademicEditor:HaifengChen Copyright?2012LydiePlouxetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Inapreviouspaper,weproposednewsilvernanoparticles(SNPs)basedantibacterialcoatingsabletoprotecteukaryoticcellsfrom SNPsrelatedtoxice?ects,whilepreservingantibacteriale?ciency.ASNPscontainingn-heptylamine(HA)polymermatrixwas depositedbyplasmapolymerizationandcoatedbyasecondHAlayer.Inthispaper,weelucidatetheantibacterialactionofthese newcoatings.WedemonstratedthatSNPs-loadedmaterialcanbecoveredbythinHApolymerlayerwithoutlosingtheantibac- terialactivitytoplanktonicbacterialivinginthenearsurroundingsofthematerial.SNPs-containingmaterialsalsorevealedanti- bacteriale?ectonadheredbacteria.Adheredbacterianumberwassigni?cantlyreducedcomparedtopureHAplasmapolymer andthephysiologyofthebacteriawasa?ected.ThenumberofadheredbacteriadirectlydecreasedwiththicknessofthesecondHA layer.Surprisingly,thequantityofcultivablebacteriaharvestedbytransfertonutritiveagardecreasednotonlywiththepresence ofSNPs,butalsoinrelationtothecoveringHAlayerthickness,thatis,oppositelytotheincreaseinadheredbacterianumber.Two hypothesesareproposedforthissurprisingresult(strongerattachmentorweakervitality),whichraisesthequestiono

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