Antioxidant Effects of Quercetin and Catechin Encapsulated into PLGA Nanoparticles英文文献资料.docVIP
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Antioxidant Effects of Quercetin and Catechin Encapsulated into PLGA Nanoparticles英文文献资料
HindawiPublishingCorporation
JournalofNanomaterials
Volume2012,ArticleID145380,12pages
doi:10.1155/2012/145380
ResearchArticle
AntioxidantEffectsofQuercetinandCatechin
EncapsulatedintoPLGANanoparticles
HectorPool,
1
DavidQuintanar,
2
JuandeDiosFigueroa,
3
CamilaMarinhoMano,
4
J.EtelvinoH.Bechara,
4
LuisA.God′?nez,
5
andSandraMendoza
1
1
2
3
4
5
DepartamentodeInvestigaci′onyPosgradoenAlimentos,FacultaddeQu′?mica,UniversidadAut′onomadeQueretaro,
76010Queretaro,Mexico
LaboratoriodePosgradoenTecnolog′?aFarmac′eutica,Divisi′ondeEstudiosdePosgrado,FacultaddeEstudiosSuperioresCuautitl′an,
UniversidadNacionalAut′onomadeM′exico,Cuautitl′anIzcalli,54740EstadodeM′exico,Mexico
DepartamentodeMaterialesBio-org′anicos,CentrodeInvestigaci′onyEstudiosAvanzadosdelInstitutoPolit′ecnicoNacional,
UnidadQueretaro,76230Queretaro,Mexico
LaboratoriodeRadicaisLivreseEstadosExcitadosenSistemasBiologicos,DepartamentodeBioqu′?mica,
UniversidadedeS?aoPaulo,05508-000S?aoPaulo,Brazil
CentrodeInvestigaci′onyDesarrolloTecnol′ogicoenElectroqu′?micaS.C.,PedroEscobedo,76703Quer′etaro,Mexico
CorrespondenceshouldbeaddressedtoSandraMendoza,smendoza@uaq.mx
Received10January2012;Revised5July2012;Accepted9July2012
AcademicEditor:MarinellaStriccoli
Copyright?2012HectorPooletal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense,
whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited.
Polymericnanoparticles(PLGA)havebeendevelopedfortheencapsulationandcontrolledreleaseofquercetinandcatechin.
Nanoparticleswerefabricatedusingasolventdisplacementmethod.Physicochemicalpropertiesweremeasuredbylightscattering,
scanning electron microscopy and ζ-potential, X-ray di?raction, infrared spectroscopy and di?erential scanning calorimetry.
Encapsulatione?ciencyandinvitroreleasepro?leswereobtainedfromdi?erentialpulsevoltammetryexperiments.Antioxidant
propertiesof free and encapsulated ?avonoids were determined by TBARS,?uorescence spectroscopy and
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