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Biventricular Pulsus Alternans英文文献资料
SAGE-HindawiAccesstoResearch
CardiologyResearchandPractice
Volume2009,ArticleID703793,3pages
doi:10.4061/2009/703793
CaseReport
BiventricularPulsusAlternans
ParamVidwanandGeorgeA.Stouffer
DivisionofCardiology,UniversityofNorthCarolina,ChapelHill,NC27599-7075,USA
CorrespondenceshouldbeaddressedtoGeorgeA.Stou?er,rstou?@
Received27April2009;Accepted27June2009
RecommendedbyGeraldMaurer
Pulsusalternansisararehemodynamicconditioncharacterizedbybeat-to-beatvariabilityinsystolicpressure.Itisattributedto
variationsinstrokevolumewithalternatecardiaccyclesandistypicallyseeninpatientswithadvancedmyopathicconditions.Left
ventricularpulsusalternansisrare,andrightventricularpulsusalternansisevenlesscommon.Thereareonlyafewreportsof
biventricularpulsusalternans.Wereportthecaseofa62-year-oldfemalewitharecentanteriorwallmyocardialinfarctionwho
hadbiventricularpulsusalternansatthetimeofcardiaccatheterization.
Copyright?2009P.VidwanandG.A.Stou?er.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution
License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly
cited.
1.CaseReport
(25mgBID),quinapril(40mgqD),andfurosemide(20mg
qD).
A62-year-oldfemalewith diabetesmellitusandhyperten-
sion developed what she thought was the “?u” associated
with orthopnea, shortness of breath, and chest pressure.
She presented to her local physician 3 weeks later when
thesymptomspersistedandwereaccompaniedbya15–20
pound weight gain. Her BNP was markedly elevated and
a chest X-ray showed cardiomegaly with bilateral pleural
e?usion. ECG and echocardiogram were consistent with a
recentanteriorwallmyocardialinfarction.
Cardiaccatheterizationaftera15pounddiuresisshowed
severely reduced left ventricular systolic function with
an ejection fraction of 31%. Left heart ?lling pressures
were elevated with a left ventricular end diastolic pressure
of 26mmHg and pulmonary capillary wedge pressure of
28mmHg. She had severe disease of the mid left ante-
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