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Bladder Cancer Detection Using Electrical Impedance Technique (Tabriz Mark 1)英文文献资料.doc

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Bladder Cancer Detection Using Electrical Impedance Technique (Tabriz Mark 1)英文文献资料

HindawiPublishingCorporation PathologyResearchInternational Volume2012,ArticleID470101,5pages doi:10.1155/2012/470101 ResearchArticle BladderCancerDetectionUsingElectricalImpedance Technique(TabrizMark1) AhmadKeshtkar, ZeinabSalehnia, AsgharKeshtkar, andBehroozShokouhi 1 1 2 3 1 2 3 MedicalPhysicsDepartment,MedicalFaculty,TabrizUniversityofMedicalSciences,Tabriz,Iran TheFacultyofEngineeringandTechnology,ImamKhomeiniInternationalUniversity(IKIU),Ghazvin,Iran ThePathologyDepartment,MedicalFaculty,TabrizUniversityofMedicalSciences,Tabriz,Iran CorrespondenceshouldbeaddressedtoAhmadKeshtkar,mpp98ak@ Received7October2011;Revised16January2012;Accepted14February2012 AcademicEditor:MarcoVolante Copyright?2012AhmadKeshtkaretal. This is an open access article distributed under the Creative Commons Attribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Bladdercanceristhefourthmostcommonmalignantneoplasminmenandtheeighthinwomen.Bladderpathologyisusually investigated visually by cystoscopy. In this technique, biopsies are obtained from the suspected area and then, after needed procedure,thediagnosticinformationcanbetaken.Thisisarelativelydi?cultprocedureandisassociatedwithdiscomfortfor thepatientandmorbidity.Therefore,theelectricalimpedancespectroscopy(EIS),aminimallyinvasivescreeningtechnique,can beusedtoseparatemalignantareasfromnonmalignantareasintheurinarybladder.Thefeasibilityofadaptingthistechniqueto screenforbladdercancerandabnormalitiesduringcystoscopyhasbeenexploredandcomparedwithhistopathologicalevaluation ofurinarybladderlesions.Exvivostudieswerecarriedoutinthisstudybyusingatotalof30measuredpointsfrommalignant and100measuredpointsfromnon-malignantareasofpatientsbladdersintermsoftheirbiopsyreportsmatchingtotheelectrical impedancemeasurements.Inallmeasurements,theimpedivityofmalignantareaofbladdertissuewassigni?cantlyhigherthan theimpe