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Camptocormia in Parkinsons Disease英文文献资料.doc

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Camptocormia in Parkinsons Disease英文文献资料

SAGE-HindawiAccesstoResearch Parkinson’sDisease Volume2010,ArticleID267640,5pages doi:10.4061/2010/267640 ResearchArticle CamptocormiainParkinson’sDisease andMasaruNotani KazuoAbe,1,2,3YutakaUchida,2 4 1 2 3 4 DepartmentofNursingandRehabilitation,KonanWomen’sUniversity,Kobe657-0001,Japan DepartmentofNeurologyandRehabilitationCenter,KonanHospital,Kobe658-0064,Japan ClinicalResearchCenter,OsakaHealthScienceUniversity,1-9-27Tenma,Kita-Ku,Osaka530-0043,Japan GaraciaHospital,RehabilitationCenter,Yokosuka562-8567,Japan CorrespondenceshouldbeaddressedtoKazuoAbe,abeneurology@ Received13November2009;Revised12February2010;Accepted2June2010 AcademicEditor:ElanD.Louis Copyright?2010KazuoAbeetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Objectives.AbnormalitiesofposturerepresentoneofthemainfeaturesofParkinson’sdisease(PD).Amongthem,camptocormia hasbeenconsideredasrareinPD.WeinvestigatedfrequencyandclinicalfeaturesofcamptocormiainPDpatients.Methods. 153PDpatients(mean68.5± 10.7yearsold,duration5.9± 2.4years)outpatientlyrecruited.Afterneurologicexamination, patientswereratedontheUni?edPDRatingScalemotorscale(UPDRSPartIII),minimentalstateexamination(MMSE).Also weevaluatedpatientswithcamptocormiabyMRI.Ofthe153PDpatients,27hadcamptocormia(meanage,67.9± 7.9yearsold; diseaseduration,6.1±3.9years).Forfurtherevaluation,werecruitedage-andsex-matched27PDpatientswithoutcamptocormia (11menand16women;meanage± SD,69.2± 10.1years,duration6.0± 2.7years)Theseselected54patientscompletedseveral self-assessments.LumbarandthoracicparaspinalmuscleswerestudiedbyEMG.Results.Therewerenosigni?cantdi?erencesin age,duration,severity,anddrugdosebetweenpatientswithandwithoutcamptocormia.AnalysisofNMSSsubitemsindicated thatPDpatientstendedtoshowlowerscoresforsleep/fatigue,attention/memory,andmiscellaneousitems.Conclusions.Wefound s