Carbon Dioxide Insufflation in Colonoscopy Is Safe A Prospective Trial of 347 Patients英文文献资料.docVIP
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Carbon Dioxide Insufflation in Colonoscopy Is Safe A Prospective Trial of 347 Patients英文文献资料
HindawiPublishingCorporation
DiagnosticandTherapeuticEndoscopy
Volume2012,ArticleID692532,4pages
doi:10.1155/2012/692532
ClinicalStudy
CarbonDioxideInsuf?ationinColonoscopyIsSafe:
AProspectiveTrialof347Patients
M.Geyer,
1U.Guller,2,3andCh.Beglinger4
1
2
3
4
GastroenterologieWettingen,Rosengartenstrasse2,5430Wettingen,Switzerland
DepartmentofOncology,Kantonsspital,9007St.Gallen,Switzerland
DepartmentofVisceralSurgeryandMedicine,UniversityHospitalBern,3010Bern,Switzerland
DepartmentofGastroenterology,UniversityHospital,4031Basel,Switzerland
CorrespondenceshouldbeaddressedtoM.Geyer,geyer@gastroenterologie-wettingen.ch
Received1June2012;Revised16August2012;Accepted29August2012
AcademicEditor:Jean-MarcDumonceau
Copyright?2012M.Geyeretal. This is an open access article distributedunder the Creative Commons AttributionLicense,
whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited.
Available evidence suggests that the use of CO2 insu?ation in endoscopy is more comfortable for the patient. The safety of
CO2useincolonoscopyremainscontentious,particularlyinsedatedpatients.Theobjectiveofthepresentprospectivetrialwas
to assess the safety of CO2 colonoscopies. Methods. 109 patients from our previous randomized CO2 colonoscopy study and
anadditional238subsequentconsecutiveunselectedpatientswhohadaroutinecolonoscopyperformedinaprivatepractice
wereenrolledfromApril2008throughSeptember2008.Allbut2patientsweresedated.Allpatientswereroutinelymonitored
withtranscutaneousCO2 measurement.VolumesofCO2 administeredwerecorrelatedwithcapnographicmeasurementsfrom
transcutaneousmonitoring.Results.Ofthe347patientsexamined,57%werewomen;mean(SD)ageofparticipantswasof60.2
years(12.8).Meanpropofoldosagewas136mg(64mg).MeanCO2valueswere34.7mmHg(5.3)atbaseline,38.9mmHg(5.5)
uponreachingtheileum,and36.9mmHg(5.0)atexamination’send.MeanmaximumincreaseofCO2 was4.5mmHg(3.6).
NocorrelationwasobservedbetweenvolumeofCO2administeredandincreasein
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