Brain MRI Segmentation with Multiphase Minimal Partitioning A Comparative Study英文文献资料.docVIP
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Brain MRI Segmentation with Multiphase Minimal Partitioning A Comparative Study英文文献资料
HindawiPublishingCorporation
InternationalJournalofBiomedicalImaging
Volume2007,ArticleID10526,15pages
doi:10.1155/2007/10526
ResearchArticle
BrainMRISegmentationwithMultiphaseMinimal
Partitioning:AComparativeStudy
ElsaD.Angelini,1TingSong,2BrettD.Mensh,3andAndrewF.Laine2
1
2
3
EcoleNationaleSup′erieuredesT′el′ecommunications,GroupedesEcolesdesT′el′ecommunications,
CNRSUMR5141,75013Paris,France
DepartmentofBiomedicalEngineering,SchoolofEngineeringandAppliedScience,ColumbiaUniversity,
NewYork,NY10027,USA
DepartmentofBiologicalPsychiatry,CollegeofPhysiciansandSurgeons,ColumbiaUniversity,NewYork,
NY10032,USA
Received3August2006;Revised10November2006;Accepted19December2006
RecommendedbyYueWang
Thispaperpresentstheimplementationandquantitativeevaluationofamultiphasethree-dimensionaldeformablemodelina
levelsetframeworkforautomatedsegmentationofbrainMRIs.Thesegmentationalgorithmperformsanoptimalpartitioning
ofthree-dimensionaldatabasedonhomogeneitymeasuresthatnaturallyevolvestotheextractionofdi?erenttissuetypes in
thebrain.Randomseedinitializationwasusedtominimizethesensitivityofthemethodtoinitialconditionswhileavoiding
theneedforaprioriinformation.Thisrandominitializationensuresrobustnessofthemethodwithrespecttotheinitialization
andtheminimizationsetup.Postprocessingcorrectionswithmorphologicaloperatorswereappliedtore?nethedetailsofthe
globalsegmentationmethod.Aclinicalstudywasperformedonadatabaseof10adultbrainMRIvolumestocomparethelevel
setsegmentationtothreeothermethods:“idealized”intensitythresholding,fuzzyconnectedness,andanexpectationmaximiza-
tionclassi?cationusinghiddenMarkovrandom?elds.Quantitativeevaluationofsegmentationaccuracywasperformedwith
comparisontomanualsegmentationcomputingtruepositiveandfalsepositivevolumefractions.Astatisticalcomparisonofthe
segmentationmethodswasperformedthroughaWilcoxonanalysisoftheseerrorratesandresultsshowedveryhighqualityand
stabilityofthemultiphasethree-dimensionallevelsetmethod.
Copyright?2007ElsaD.Angelinietal. Th
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