- 1、本文档共2页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 5、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 6、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
An Age-Old Problem 英文参考文献
Editorial
AnAge-OldProblem
Nicholas Katsanis*, Susan M.Rosenberg
Contravimmortisnoncrescitherbainhortis.
‘‘Thereisnoherbinthegardensagainstthe
powerofdeath.’’—KingSigismundIII
(1566–1632)onhisdeathbed
R
apidadvancesinthebasicand
medicalsciences,whilerapidly
expandingourknowledgebase
onahostofphysiologicalprocesses
(andtheircellularandorganismal
consequenceswhendisrupted),arealso
posingasigni?cantburden.Thesheer
volumeofinformationamassedfroma
hostofexperimentalsystemsand
modelorganismscanrepresenta
dauntingassimilationtasktoboththe
neophyteandtheexperienced
doi:10.1371/journal.pgen.0030037.g001
investigator,aproblemoften
compoundedbycontradictoryand/or
con?ictingdatathatareinherenttothe
constant?uxofscienti?cdiscovery.
Withthesechallengesinmind,we
arepleasedtointroduceanewseries
initiativebyPLoSGenetics.Inkeeping
withthemissionstatementofour
journaltopresentinterdisciplinary
researchinthebroadestpossible
context,wehavecommissionedaseries
ofReviewandOpinionarticlesbound
thematicallytoadiscretesetoftopics
ofinherentcomplexity,aswellasbroad
interest.Eachcomponentoftheseries
willexamineafacetofthechosen
problemandwehopethattheamalgam
ofeachseries,whichwillbeavailable
electronicallyasauni?edentity,will
botheducatethenon-specialistaswell
asprovideabalancedviewthatwill
transmittoourreadershipan
ALookattheSciencebehindtheGeneticsofAging
(Image:photographkindlyprovidedbytheKeanefamily,PLoSBiology4[4]:e119)
understandwhyorganismsage,which
inturnmightoffercluesastohowone
mightdecelerate,stop,orevenreverse
thisprocess.Whenexaminingthe?eld
ofagingresearch,wecanidentifythree
majorspheres:cellularaging
(senescence/quiescence),organismal
aging,andage-relateddisorders.Inthis
series,wewillfocusprimarilyofthe
?rsttwoareas,becausethestudyof
age-relateddisordersdoesnot
necessarilyinformthebasicquestions,
namely:(a)whatarethebasic
determinantsoflifespan,and(b)what
arethefundamentalcellularand
molecularmechanismsthatunderscore
agingprocesses?
obviousincaptivitywherenatural
hazardisremov
您可能关注的文档
- Altered Regional Homogeneity in the Development of Minimal Hepatic Encephalopathy A Resting-State Functional MRI Study 英文参考文献.doc
- Altered Plasma Apolipoprotein Modifications in Patients with Pancreatic Cancer Protein Characterization and Multi-Institutional Validation 英文参考文献.doc
- Altered Regulation of Akt Signaling with Murine Cerebral Malaria, Effects on Long-Term Neuro-Cognitive Function, Restoration with Lithium Treatment 英文参考文献.doc
- Altered Resting State in Diabetic Neuropathic Pain 英文参考文献.doc
- Altered Retinoic Acid Metabolism in Diabetic Mouse Kidney Identified by 18O Isotopic Labeling and 2D Mass Spectrometry 英文参考文献.doc
- Altered PI3-KinaseAkt Signalling in Skeletal Muscle of Young Men with Low Birth Weight 英文参考文献.doc
- Altered Serotonin, Dopamine and Norepinepherine Levels in 15q Duplication and Angelman Syndrome Mouse Models 英文参考文献.doc
- Altered Neuronal Intrinsic Properties and Reduced Synaptic Transmission of the Rat's Medial Geniculate Body in Salicylate-Induced Tinnitus 英文参考文献.doc
- Alternaria-Induced Release of IL-18 from Damaged Airway Epithelial Cells An NF-κB Dependent Mechanism of Th2 Differentiation 英文参考文献.doc
- Altered Spontaneous Activity in Anisometropic Amblyopia Subjects Revealed by Resting-State fMRI 英文参考文献.doc
最近下载
- HG╱T 3655-2012 紫外光(UV)固化木器涂料.pdf
- 人民警察警示教育观看心得.docx VIP
- Q-GDW-智能变电站辅助控制系统设计技术规范.pdf
- 外教社2023中国文化英语综合教程 上册 Unit 3 PPT课件(试用版).pptx
- 乡镇临床执业助理医师:甲状腺功能亢进症考试题.docx VIP
- 冀教版七年级上册数学《角的大小》教学说课研讨课件复习.pptx VIP
- 全国智能制造应用技术技能竞赛题及答案.doc VIP
- 智慧园区管理平台建设方案.pdf
- XX职业技术学院关于大数据与会计专业实习的实施方案.docx
- GBT 50034-2024 建筑照明设计标准.docx VIP
文档评论(0)