Estimating Population Cause-Specific Mortality Fractions from in-Hospital Mortality Validation of a New Method 英文参考文献.docVIP

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Estimating Population Cause-Specific Mortality Fractions from in-Hospital Mortality Validation of a New Method 英文参考文献.doc

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Estimating Population Cause-Specific Mortality Fractions from in-Hospital Mortality Validation of a New Method 英文参考文献

o PL SMEDICINE EstimatingPopulationCause-Specific MortalityFractionsfromin-HospitalMortality: ValidationofaNewMethod Christopher J.L.Murray1*,Alan D.Lopez2,Jeremy T.Barofsky3,Chloe Bryson-Cahn3,Rafael Lozano4 1 Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, United States of America, 2 School of Population Health, University of Queensland,Herston,Queensland,Australia,3HarvardInitiativeforGlobalHealth,Cambridge,Massachusetts,UnitedStatesofAmerica,4DirectorGeneraldeInformacio′n, Secreter?′adeSalud,MexicoDF,Mexico Funding:Thisprojectwasfunded,in part,throughtheGrandChallenges inGlobalHealthInitiative(http:// /channels/gcgh).This projectwasalsofundedinpartby USNationalInstituteonAginggrant #PO1AG17625‘‘GlobalBurdenof Disease2000inAgingPopulations.’’ Thefundershadnoroleinstudy design,datacollectionandanalysis, decisiontopublish,orpreparation ofthemanuscript. ABSTRACT Background Cause-of-deathdataformanydevelopingcountriesarenotavailable.Informationondeaths in hospital by cause is available in many low- and middle-income countries but is not a representative sample of deaths in the population. We propose a method to estimate population cause-specific mortality fractions (CSMFs) using data already collected in many middle-income and some low-income developing nations, yet rarely used: in-hospital death records. CompetingInterests:Theauthors havedeclaredthatnocompeting interestsexist. MethodsandFindings AcademicEditor:PeterByass,Umea? University,Sweden For a given cause of death, a community’s hospital deaths are equal to total community deaths multiplied by the proportion of deaths occurring in hospital. If we can estimate the proportion dying in hospital, we can estimate the proportion dying in the population using deathsinhospital.Weproposetoestimatetheproportionofdeathsforanage,sex,andcause groupthatdieinhospitalfromthesubsetofthepopulationwherevitalregistrationsystems function or from another population. We evaluated ou