Health Centre Surveys as a Potential Tool for Monitoring Malaria Epidemiology by Area and over Time 英文参考文献.docVIP
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Health Centre Surveys as a Potential Tool for Monitoring Malaria Epidemiology by Area and over Time 英文参考文献
HealthCentreSurveysasaPotentialToolforMonitoring
MalariaEpidemiologybyAreaandoverTime
AbrahamR.Oduro1,2*,KalifaA.Bojang1,DavidJ.Conway1,2,TumaniCorrah1,BrianM.Greenwood2,
DavidSchellenberg2
1MedicalResearchCouncilLaboratories,Banjul,TheGambia,2LondonSchoolofHygieneandTropicalMedicine,London,UnitedKingdom
Abstract
Background: Presently, many malaria control programmes use health facility data to evaluate the impact of their
interventions.Facility-basedmalariadata,althoughuseful,haveproblemswithcompleteness,validityandrepresentative-
nessandrelianceonroutinelycollectedhealthfacilitydatamightunderminedemonstrationofthemagnitudeoftheimpact
of the recent scaleups of malaria interventions. To determine whether carefully conducted health centre surveys canbe
reliablemeansofmonitoringareaspecificmalariaepidemiology,wehavecomparedmalariaspecificindicesobtainedfrom
surveysinhealthcentreswithindicesobtainedfromcross-sectionalsurveysconductedintheircatchmentcommunities.
Methods:Aseriesofagestratified,seasonal,cross-sectionalsurveyswereconductedduringthepeakmalariatransmission
seasonin2008andduringthefollowingdryseasonin2009insixecologicallydiverseareasinTheGambia.Participantswere
patientswhoattendedthehealthcentresplusarepresentativesamplefromthecatchmentvillagesofthesehealthfacilities.
Parasitaemia,anaemia,attributableproportionoffeverandanti-MSP1-19 antibody seroprevalencewerecomparedinthe
healthfacilityattendeesandcommunityparticipants.
Results:Atotalof16,230subjectscompletedthestudy;approximatelyhalfparticipatedinthehealthcentresurveysand
halfinthewetseasonsurveys.Datafromboththehealthcentreandcommunitysurveysshowedthatmalariaendemicityin
TheGambiaisnowlow,heterogeneousandseasonal.Inthewetseason,parasitaemia,seroprevalenceandfeverprevalence
werehigherinsubjectsseeninthehealthcentresthaninthecommunitysurveys.Agepatternsofparasitaemia,attributable
proportionsoffeverandseroprevalenceratesweresimilarinsubjectswhoparticipatedinthecommunityandhealthcentre
surveys.
Conclusio
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