Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis 英文参考文献.docVIP

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Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis 英文参考文献.doc

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Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis 英文参考文献

MouseGenome-WideAssociationandSystemsGenetics IdentifyAsxl2AsaRegulatorofBoneMineralDensity andOsteoclastogenesis CharlesR.Farber1,2,3*,BrianJ.Bennett4,LuzOrozco4,WeiZou5,AnaLira1,EmrahKostem6,HyunMin Kang6,NicholasFurlotte6,AniBerberyan4,AnatoleGhazalpour4,JaijamSuwanwela7,ThomasA.Drake8, EleazarEskin6,Q.TianWang9,StevenL.Teitelbaum5,AldonsJ.Lusis4,10,11 1Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America, 2Department of Medicine, Division of Cardiovascular Medicine, University of Virginia, Charlottesville, Virginia, United States of America, 3Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville,Virginia,UnitedStatesofAmerica,4DepartmentofMedicine,DavidGeffenSchoolofMedicine,UniversityofCaliforniaLosAngeles,LosAngeles,California, United States of America, 5Department of Pathology and Immunology, School of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America,6DepartmentofComputerScience,UniversityofCaliforniaLosAngeles,LosAngeles,California,UnitedStatesofAmerica,7DepartmentofOralBiology,David GeffenSchoolofMedicine,UniversityofCaliforniaLosAngeles,LosAngeles,California,UnitedStatesofAmerica,8DepartmentofPathologyandLaboratoryMedicine, DavidGeffenSchoolofMedicine,UniversityofCaliforniaLosAngeles,LosAngeles,California,UnitedStatesofAmerica,9DepartmentofBiologicalSciences,Universityof IllinoisatChicago,Chicago,Illinois,UnitedStatesofAmerica,10DepartmentofHumanGenetics,DavidGeffenSchoolofMedicine,UniversityofCaliforniaLosAngeles, LosAngeles,California,UnitedStatesofAmerica,11DepartmentofMicrobiology,Immunology,andMolecularGenetics,UniversityofCaliforniaLosAngeles,LosAngeles, California,UnitedStatesofAmerica Abstract Significant advances have been made in the discovery of genes affecting bone mineral density (BMD); however, our understanding of its genetic basis remains incomplete. In the current study, genome-wide association (GWA) a