Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome 英文参考文献.docVIP

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Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome 英文参考文献.doc

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Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome 英文参考文献

Open Access Re arch 2006BergmanetVoal.lusee 7, Issue 11, Article R112 Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome Casey M Bergman*?, Hadi Quesneville?, Dominique Anxolabéhère§ and Michael Ashburner* Addresses: *Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. ?Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK. ?Laboratoire de Bioinformatique et Génomique, Institut Jacques Monod, place Jussieu, 75251 Paris cedex 05, France. §Laboratoire Dynamique du Génome et évolution, Institut Jacques Monod, place Jussieu, 75251 Paris cedex 05, France. Correspondence: Casey M Bergman. Email: casey.bergman@manchester.ac.uk Published: 29 November 2006 Received: 31 July 2006 Revised: 13 November 2006 Accepted: 29 November 2006 Genome Biology 2006, 7:R112 (doi:10.1186/gb-2006-7-11-r112) The electronic version of this article is the complete one and can be found online at /2006/7/11/R112 ? 2006 Bergman et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. NetworkslapnceAnsyasnteaofmlytransposablesaigsaoifnhstigthh-eremselementsoajlourtiotynotfrinatrnaflysposablensposablelemente elemenannotationsts families ininthDrosophilae fly./p melanogaster suggests the existence of a global surveil- Abstract Background: The recent availability of genome sequences has provided unparalleled insights into the broad-scale patterns of transposable element (TE) sequences in eukaryotic genomes. Nevertheless, the difficulties that TEs pose for genome assembly and annotation have prevented detailed, quantitative inferences about the contribution of TEs to genomes sequences. Results: Using a high-resolution ann