Rubella seroprevalence among primary and pre- primary school pupils at Mois Bridge location, Uasin Gishu District, Kenya 英文参考文献.docVIP

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Rubella seroprevalence among primary and pre- primary school pupils at Mois Bridge location, Uasin Gishu District, Kenya 英文参考文献.doc

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BMC Public Health BioMedCentral Research article Open Access Rubella seroprevalence among primary and pre- primary school pupils at Mois Bridge location, Uasin Gishu District, Kenya Janeth J Kombich*, Paul C Muchai, Peter Tukei and Peter K Borus Address: Centre for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya Email: Janeth J Kombich* - jkombich@; Paul C Muchai - pmuchai@; Peter Tukei - ptukei@; Peter K Borus - pborus@ * Corresponding author Published: 29 July 2009 Received: 19 August 2008 Accepted: 29 July 2009 BMC Public Health 2009, 9:269 doi:10.1186/1471-2458-9-269 This article is available from: /1471-2458/9/269 ? 2009 Kombich et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rubella is an infectious and generally mild childhood viral disease. The disease is of public health importance because infection acquired during early pregnancy often results in foetal abnormalities that are classified as congenital rubella syndrome (CRS). The burden of rubella infection in most developing countries in not well documented because of limited epidemiological data. However, availability of an effective vaccine has made it necessary to have all the countries with no routine vaccination schedule to evaluate the burden of disease in order to make informed decisions on rubella vaccination and strategy. To address this gap we conducted a study to determine age-specific rubella seroprevalence rates and related risk factors among primary and pre-primary school children in Uasin Gishu district, Mois Bridge location of Kenya. Methods: Subjects of the study were 498 pupils from seven primary schools aged 4–20 years. Questionnaire surveys with blo