Selective decontamination of the digestive tract all questions answered 英文参考文献.docVIP

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Selective decontamination of the digestive tract all questions answered 英文参考文献.doc

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Selective decontamination of the digestive tract all questions answered 英文参考文献

Available online /content/7/3/203 Commentary Selective decontamination of the digestive tract: all questions answered? Marc JM Bonten1, Hans CA Joore2, Bartelt M de Jongh3, Jan Kluytmans4, Ed J Kuijper5, Henk J van Leeuwen2, Anne Marie GA de Smet6 and Christina Vandenbroucke-Grauls7 1Internist, Infectious Disease Specialist, Department of Internal Medicine Dermatology, Division of Acute Internal Medicine Infectious Diseases, University Medical Center Utrecht, The Netherlands 2Internist, Intensivist, Department of Internal Medicine Dermatology, Division of Acute Internal Medicine Infectious Diseases, University Medical Center Utrecht, The Netherlands 3Medical Microbiologist, Laboratory of Medical Microbiology, Antonius Hospital Nieuwegein, The Netherlands 4Medical Microbiologist, Laboratory for Microbiology and Infection Control, Amphia Hospital, Breda, The Netherlands 5Medical Microbiologist, Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands 6Anaesthetist, Intensivist, Department of Peri-Operative and Emergency Care, Division of Anesthesiology, University Medical Center Utrecht, The Netherlands 7Medical Microbiologist, Department of Medical Microbiology, VU University Medical Center, Academic Medical Center, Amsterdam, The Netherlands Correspondence: Marc JM Bonten, m.j.m.bonten@digd.azu.nl Published online: 24 January 2003 Critical Care 2003, 7:203-205 (DOI 10.1186/cc1881) This article is online at /content/7/3/203 ? 2003 BioMed Central Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X) Abstract Although many studies have shown beneficial effects of SDD on the incidence of respiratory tract infections, SDD did not become routine practice because mortality reduction was not demonstrated in individual trials, beneficial effects on duration of ventilation, ICU stay or hospital stay were not demonstrated, cost-efficacy had not been demonstrated, and selection of an