Serological Response to the 2009 Pandemic Influenza A (H1N1) Virus for Disease Diagnosis and Estimating the Infection Rate in Thai Population 英文参考文献.docVIP

Serological Response to the 2009 Pandemic Influenza A (H1N1) Virus for Disease Diagnosis and Estimating the Infection Rate in Thai Population 英文参考文献.doc

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Serological Response to the 2009 Pandemic Influenza A (H1N1) Virus for Disease Diagnosis and Estimating the Infection Rate in Thai Population 英文参考文献

SerologicalResponsetothe2009PandemicInfluenzaA (H1N1)VirusforDiseaseDiagnosisandEstimatingthe InfectionRateinThaiPopulation HatairatLerdsamran1,ChakraratPittayawonganon2,PhisanuPooruk1,AnekMungaomklang3 ,Sopon Iamsirithaworn2,PrasertThongcharoen1,UraiwanKositanont1,PrasertAuewarakul1 ,Kulkanya Chokephaibulkit4,SineenatOota5,WarinPongkankham6,PatummalSilaporn2,SupaloekKomolsiri1, PiromNoisumdaeng1,TaweeChotpitayasunondh7,ChariyaSangsajja8,WitthawatWiriyarat9 ,Suda Louisirirotchanakul1,PilaipanPuthavathana1* 1Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok,Thailand, 2Bureau of Epidemiology, Department of Disease Control, MinistryofPublicHealth,Nonthaburi,Thailand,3MaharatNakhonratchasimaHospital,MinistryofPublicHealth,Nakhonratchasima,Thailand,4DepartmentofPediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 5The National Blood Center, The Thai Red Cross Society, Bangkok, Thailand, 6Division of PreventiveMedicine,NavalMedicalDepartment,RoyalThaiNavy,ChonBuri,Thailand,7QueenSirikitNationalInstituteofChildHealth,MinistryofPublicHealth,Bangkok, Thailand, 8Bamrasnaradura Infectious Disease Institute, Ministry of Public Health, Nonthaburi, Thailand, 9Faculty of Veterinary Science, Mahidol University, Nakhon Pathom,Thailand Abstract Background: Individuals infected with the 2009 pandemic virus A(H1N1) developed serological response which can be measuredbyhemagglutination-inhibition(HI)andmicroneutralization(microNT)assays. Methodology/PrincipalFindings:MicroNTandHIassaysforspecificantibodytothe2009pandemicviruswereconducted inserumsamplescollectedattheendofthefirstepidemicwavefromvariousgroupsofThaipeople:laboratoryconfirmed cases,blooddonorsandhealthcareworkers(HCW)inBangkokandneighboringprovince,generalpopulationintheNorth andtheSouth,aswellasarchivalseracollectedatpre-andpost-vaccinationfromvaccineeswhoreceivedinfluenzavaccine ofthe2006season.Thisstudydemonstratedthatgooseerythrocytesyiel

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