Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients 英文参考文献.docVIP

下载本文档

4
0
约2.26万字
约 5页
2017-05-13 发布于上海
举报
版权申诉

Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients 英文参考文献.doc

1、本文档共5页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients 英文参考文献

Available online /content/9/2/R139 Research Open Access April 2005 Vol 9 No 2 Serum cystatin C concentration as a marker of acute renal dysfunction in critically ill patients Patricia Villa1, Manuel Jiménez1, Maria-Cruz Soriano1, Jesus Manzanares1 and Pilar Casasnovas2 1Intensive Care Unit, Hospital Universitario La Paz, Madrid, Spain 2Biochemistry Unit, Hospital Universitario La Paz, Madrid, Spain Corresponding author: Manuel Jiménez, majilen@yahoo.es Received: 4 June 2004 Critical Care 2005, 9:R139-R143 (DOI 10.1186/cc3044) This article is online at: /content/9/2/R139 Revisions requested: 26 July 2004 Revisions received: 25 October 2004 Accepted: 17 December 2004 Published: 7 February 2005 ? 2005 Villa et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/ licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction In critically ill patients sudden changes in glomerular filtration rate (GFR) are not instantly followed by parallel changes in serum creatinine. The aim of the present study was to analyze the utility of serum cystatin C as a marker of renal function in these patients. Methods Serum creatinine, serum cystatin C and 24-hour creatinine clearance (C ) were determined Cr in 50 critically ill patients (age 21–86 years; mean Acute Physiology and Chronic Health Evaluation II score 20 ± 9). They did not have chronic renal failure but were at risk for developing renal dysfunction. Serum cystatin C was measured using particle enhanced immunonephelometry. Twenty-four-hour body surface adjusted CCr was used as a control because it is the gold standard for determining GFR. Results Serum creatinine, serum cystatin C and C (mean ± standard deviation [range]) were 1.00 ± Cr 0.85 mg/dl (0.40–5.61 mg/dl), 1.19 ± 0.79 mg/l (0.49–4.70 mg/l), and 92.74 ± 52.74 ml/min p