Seroprevalence of HIV, hepatitis b, and hepatitis c among opioid drug users on methadone treatment in the netherlands 英文参考文献.docVIP
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Seroprevalence of HIV, hepatitis b, and hepatitis c among opioid drug users on methadone treatment in the netherlands 英文参考文献
Schreuderetal.HarmReductionJournal2010,7:25
/content/7/1/25
BRIEF REPORT
OpenAccess
SeroprevalenceofHIV,hepatitisb,andhepatitis
camongopioiddrugusersonmethadone
treatmentinthenetherlands
ImkeSchreuder1,2*,MarianneABvanderSande2,6,MattydeWit3,MoniqueBongaerts4,CharlesABBoucher1,
EstherACroes5,MaaikeGvanVeen2
Abstract
Background:Injectingdrugusers(IDU)remainanimportantpopulationatriskforblood-borneinfectionssuchas
humanimmunodeficiencyvirus(HIV),hepatitisBvirus(HBV)andhepatitisCvirus(HCV).IntheNetherlands,a
programisbeingimplementedtoofferannualvoluntaryscreeningfortheseinfectionstoopioiddrugusers
(ODUs)screenedinmethadonecare.Attwocaresiteswheretheprogramisnowoperating,ourstudyaimedto
estimatetheseroprevalenceamongODUsscreenedforHIV,HBVandHCV;toevaluateHBVvaccinationcoverage;
andtoassessthefeasibilityofmonitoringseroprevalencetrendsbyusingroutineannualscreeningdata.
Methods:Opioiddrugusersonmethadonetreatmentareroutinelyofferedvoluntaryscreeningforinfectious
diseasessuchasHIV,HBVandHCV.Dataonuptakeandoutcomeofanti-HIV,anti-HBc,andanti-HCVscreening
amongODUsreceivingmethadonewereobtainedfromtworegions:Amsterdamfrom2004to2008andHeerlen
from2003to2009.
Findings:AnnualscreeninguptakeforHIV,HBVandHCVvariedfrom34to69%,dependingondiseaseand
screeningsite.Ofusersscreened,2.5%wereHIV-positiveinAmsterdamand11%inHeerlen;26%wereHCV-
positiveinAmsterdamand61%inHeerlen.OfthosescreenedforHBV,evidenceofcurrentorpreviousinfection
(anti-HBc)wasfoundamong33%inAmsterdamand48%inHeerlen.InAmsterdam,92%werefullyvaccinatedfor
HBVversus45%inHeerlen.
Conclusion:AnnualscreeningforinfectiousdiseasesinallODUsinmethadonecareisnotfullyimplementedin
theNetherlands.Onaverage,morethanhalfoftheODUsinmethadonecareinHeerlenandAmsterdamwere
screenedforHIV,HBVandHCV.Inaddition,screeningdataindicatethatHBVvaccinationuptakewasratherhigh.
WhiletheHIVprevalenceamongtheseODUswasrelativelylowcomparedtootherdrug-usingpopulations,the
highHCVprevalenceamongthisgroupunderscorestheneedtoexpandannualscreeningandint
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