Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites 英文参考文献.docVIP

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Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites 英文参考文献.doc

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Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites 英文参考文献

Open Access Re rch 2004HarcusetVoal.lumesea5, Issue 6, Article R39 Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites Yvonne M Harcus*, John Parkinson*?, Cecilia Fernández*§, Jennifer Daub*, Murray E Selkirk?, Mark L Blaxter* and Rick M Maizels* Addresses: *Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh, EH9 3JT, UK. ?Department of Biological Sciences, Imperial College London, London SW7 2AZ, UK. ?Current address: Program in Genetics and Genomic Biology, Hospital for Sick Children, University Avenue, Toronto, Ontario M5G 1X8, Canada. §Current address: Facultad de Química, Cátedra de Inmunología, Universita de la Republica, Montevideo 11300, Uruguay. Correspondence: Rick M Maizels. E-mail: rick.maizels@ed.ac.uk Published: 18 May 2004 Received: 30 December 2003 Revised: 14 April 2004 Accepted: 29 April 2004 Genome Biology 2004, 5:R39 The electronic version of this article is the complete one and can be found online at /2004/5/6/R39 ? 2004 Harcus et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Signalthneropoitsnynts.Pgiliyae/nlrsequencepuhapsosasibrttira.sasAmsitmiliisoeanalysisnagshisiguhc/hlyioftasduiexpressedascpcateawstseifoluln-lssmtiusequencesodtdiheedosmfelciofrdeetagsetailonnndefromomofnapetrottheohdtaetipnematoderaserqcauaspirtaebsolsefuNippostrongylusroioftdemsenoodtfsig,feywninhegicaohdrasmpebrasiliensisctaarnteiitopenusslpatrtooindpgueandrtchmtseikththensouoswrtevolutionveninvtvaoilrmwoniotmdhofuienlnasecretedatt.ephoitoesntNtiimpro-allyppos-mu Abstract Background: Parasitism is a highly successful mode of life and one that requires suites of gene adaptations to permit survival within a potentially hostile host.