Skin testing versus radioallergosorbent testing for indoor allergens 英文参考文献.docVIP

Clinical and Molecular Allergy BioMedCentral Research Open Access Skin testing versus radioallergosorbent testing for indoor allergens Birjis Chinoy, Edgar Yee and Sami L Bahna* Address: Allergy and Immunology Section, Louisiana State University Health Sciences Center; Shreveport, Louisiana, USA Email: Birjis Chinoy - info@; Edgar Yee - the.yees@; Sami L Bahna* - sbahna@ * Corresponding author Published: 15 April 2005 Received: 27 January 2005 Accepted: 15 April 2005 Clinical and Molecular Allergy 2005, 3:4 doi:10.1186/1476-7961-3-4 This article is available from: /content/3/1/4 ? 2005 Chinoy et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. AllergySkin testingRASTSpecific IgEMiteCockroachCatDog Abstract Background: Skin testing (ST) is the most common screening method for allergy evaluation. Measurement of serum specific IgE is also commonly used, but less so by allergists than by other practitioners. The sensitivity and specificity of these testing methods may vary by type of causative allergen and type of allergic manifestation. We compared ST reactivity with serum specific IgE antibodies to common indoor allergens in patients with respiratory allergies. Methods: 118 patients (3 mo-58 yr, mean 12 yr) with allergic rhinitis and/or bronchial asthma had percutaneous skin testing (PST) supplemented by intradermal testing (ID) with those allergens suspected by history but showed negative PST. The sera were tested blindly for specific IgE antibodies by the radioallergosorbent test (Phadebas RAST). The allergens were D. farinae (118), cockroach (60), cat epithelium (90), and dog epidermal (90). Test results were scored 0–4; ST≥ 2 + and RAST≥ 1 + were considered positive