Stem cell banking between traceability and identifiability 英文参考文献.docVIP

Knoppers and Isasi Genome Medicine 2010,2:73 /content/2/10/73 REVIEW Stem cell banking: between traceability and identiability Bartha M Knoppers* and Rosario Isasi successful model system for drug discovery, including the Abstract development of new testing methods for drug e?cacy, toxicity and safety, and provide a deeper understanding of the processes of human cell di?erentiation and develop- ment for the treatment of diseases such as cancer [1]. Given the scienti?c potential of the ?eld, stem cell banks are increasingly seen as an essential resource of biological materials for both basic and translational research. Stem cell banks and registries support trans- national access to quality-controlled and ethically sourced stem cell lines from di?erent origins and of varying grades - for example, research versus clinical. ey are also the ‘de facto’ depositories of ‘biological standards’ [2]. According to the Organisation for Economic Co- operation and Development, advances in regenerative medicine and stem cells are leading to the development of a bio economy: ‘a world where biotechnology contri- butes to a signi?cant share of economic output’ [3]. Conse quently, stem cell banks are destined to constitute a pillar of the bioeconomy of many countries. Stem cell banks are increasingly seen as an essential resource of biological materials for both basic and translational research. Stem cell banks support transnational access to quality-controlled and ethically sourced stem cell lines from dierent origins and of varying grades. According to the Organisation for Economic Co-operation and Development, advances in regenerative medicine are leading to the development of a bioeconomy,‘a world where biotechnology contributes to a signicant share of economic output’. Consequently, stem cell banks are destined to constitute a pillar of the bioeconomy in many