Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients an observational study 英文参考文献.docVIP

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Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients an observational study 英文参考文献.doc

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Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients an observational study 英文参考文献

Available online /content/13/4/R133 Research Open Access Vol 13 No 4 Transpulmonary thermodilution-derived cardiac function index identifies cardiac dysfunction in acute heart failure and septic patients: an observational study Simon Ritter1, Alain Rudiger2 and Marco Maggiorini2 1Intensive Care Unit, Department of Internal Medicine, Triemli City Hospital, Birmensdorferstrasse 497, CH-8063 Zurich, Switzerland 2Intensive Care Unit, Department of Internal Medicine, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland Corresponding author: Alain Rudiger, alain.rudiger@usz.ch Received: 5 May 2009 Revisions requested: 4 Jun 2009 Revisions received: 6 Jul 2009 Accepted: 11 Aug 2009 Published: 11 Aug 2009 Critical Care 2009, 13:R133 (doi:10.1186/cc7994) This article is online at: /content/13/4/R133 ? 2009 Ritter et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction There is limited clinical experience with the single- indicator transpulmonary thermodilution (pulse contour cardiac output, or PiCCO) technique in critically ill medical patients, particularly in those with acute heart failure (AHF). Therefore, we compared the cardiac function of patients with AHF or sepsis using the pulmonary artery catheter (PAC) and the PiCCO technology. Results Compared to septic patients, AHF patients had a significantly lower cardiac index, cardiac function index (CFI), global ejection fraction, mixed venous oxygen saturation (SmvO ) and pulmonary vascular permeability index, but higher 2 pulmonary artery occlusion pressure. All patients with a CFI less than 4.5 per minute had an SmvO not greater than 70%. In both 2 groups, the CFI correlated with the left ventricular