伴全身多处转移的头部血管肉瘤1例.pdfVIP

…在;253| 在if在血气需品在1927 伴全身多处转移的头部血管肉瘤 1 例 王婷婷l ，叶云霞2 ，王琳1 ，刘宏杰l ，夏金龙1 亭，郭在培l [摘 要] 患者男，53 岁。头部丘莎 1 年，肿块5 个月。组织病理:真皮内可见内含红细胞的不规则管舷相互融 合，浸润生长，管腔衬附细胞大小不一，核大深染，胞浆丰富，核分裂易见，异型性明显。兔疫组化z CD31 ， CD34 阳性;5-1oo ， 5MA， Des 阴性。诊断:血管肉瘤。经重组人血管内皮抑制素注射液及萦衫尊 方案化疗 10 周期后皮损缩小，因无手术切除指征，遂予局部放疗。 4 个月前患者右小腿出现一包块， 术后病理证实为血管肉瘤。 1 个月前ÌET/CT 示右小腿肌组织、左侧腮腺、盆腔、右侧复股沟至属寓淋 巴结、右侧月在骨头均考虑恶性病变。行长春瑞滨、顺钧Ã重组人血管内皮抑制素注射液化疗。 [关键词] 头部:血管肉瘤;转移 [中图分类号] R 739. 5 [文献标识码] B [文章编号] 1∞1 -7089(2012) 10-ω27-但 AC础。f Aogiosarcoma of the Scalp complicated wi也 multiple metas恼:is WANG Ting-ting 1 ,YE Yun-xia2 ,WANG Lin ,LlU Hong-jie ,XIA Jin-Io吨1· ， GUO Zai-peit 唱， (1. Department of Dermatovenereology , West China Hospi时， Sichuan university ,Che咱也61仪剧，CJμmz2. 挠和切Je1Il 01 Pathology , West China Hospital ,Sichuan university , Chengdu 61∞41 ， China 川Department ofDerma归，logy， Chinae Mo副秘方ae Hospital of Hechuan ,Hechuan 401520 , Chian) [ Correspoodiog author] LIU Hong-jie ,E-mail: hongjieI12@ [ Abstract] A 53叩ar-old male have presented with papules on head for one ye町，m嗣s for five n阳nths. Pathol吨pcal ex- amnation showed luminallining attached cells were of different sizes ,with ahundant cy切plasm ， prominent DU- clei with mitosis and significant atypia. lmmunohistochemical staining showed that the 饱mor cells ex严esøed CD31 and CD34 ,did not express 5-1∞，5MA and Des. The dia喜nOSIS W幽 anglO随rcoma. After 10 cycl田。r recombinant human endostatin and paclitaxel chemotherapy ,skin lesions of patients were 归rtially remi能00. 四ere was no surgical resection indicated ,so the patient was given local radiotherapy. Four mon也咿，趾 skin lesitts relapsed with a mass on the right leg ,which wa