105例静脉滴注致新的严重的药品不良反应病例报告分析.pdfVIP

中国药物警戒第7 卷第4 期 2010~4 月 April , 2010, Vol.7 , No .4 中阁分类号:R994.11 文献标识码:A 文章编号:1672叩8629(2010)04…0240-03 105 例静脉滴注致新的严重的药品不良反应病例报告分析 静芸芸孟庆义赵云(山东省l临邑县食品药品监督管理局山东德州 2515ω) 摘要:目的通过分析 105 例因静脉滴油引起的新的、严寰的药品不良反应病例报告，为l 临床安全合理用药提供参考 侬掘。方法采用四顾性研究方法，对临邑县2ω9 年收集的 105 例经静脉滴注引起的新的、严重的病例报告进行分 类汇总及分析评价。结果中老年人不良反应所占比例最高，引也药品不良反应的品种吏要是抗微生物葫物，累及 17 个系统m 器官，涉及国家基本药物35 个。结论临床必须重视静脉滴注不良反应的日在测，以减少或避免严重药品不 良反应的发生。 关键询:静脉捕、注;不良反应;分析 Analysis of 105 问eports of New Adverse Reactíons Caused by Injectíon JING Yun-yun MENG Qing-yi ZHAO Yun (LinYi Food and Drug Administration , Shandong Dezhou 251500) Abstract: Objectíve To ana1yze the 105 reports of new adverse reactions caused by injection , provide reference for clinical application and quality control. Methods 105 ADR reports collected by Linyi County for ADR Monitoring were analyzed using retrospective study method 丘om January to December 2009. Results High ADR occurrence was a1so observed in the old patie附. Most of AD队 were antimicrobia1 drugs. 17 organs systerns were involved. It involved 35 k:inds of national essential drugs. Conclusion ADR caused by injection shou1d be monitored so as to reduce or avoid severe ADR. Key words:injection; adverse drug reaction(ADR); analysis 静脉滴由是l临床上最常用的给药谶径，因其能以最 袋 1 ADR 涉及的报告提型 高放度和最快遮度到达靶器官，但同时也是最危险的给 男(n) 女(n) 合计(n) 构成比(%) 药途径(1)。经静脉滴往后，由于药物直接j投入血液循环， 。 -10 8 6 14 13.33 11-20 4 3 7 6.67 在且连发挥疗效的同时也增加了药品不良反应(ADR)