严重感染与慢性重型病毒性肝炎预后关系分析.pdfVIP

National Medical Frontiers ofChina, Oct 2010 , Vo l.5 No.19 中阂医疗前活 2010年10月 第5~量第19期 论萄. 5 严重感染与慢性重现病毒性肝炎预后关系分析 张字镣朱翔真志砸 {摘要1 阔的探讨慢性重型病毒性肝炎患者严重感染与预后的关系。方法回顾性调褒慢性爱级病毒性肝炎住院怠者101 例。 按是否存在严重感染分为感染组与非感染纽;同时按不同预后分为存活组与死亡纽。比较感染组与非感染组之间肝肾功能、 P丁A、成常规、死亡牟差异;比较存活级与死亡级之间感染学、itt 白细胞在史差异巳储来:t~肝炎感染级患者血清丁BIL、 cd号 子排感染纽患者俨值分别为oβ13、 0.(01) ，感染组怠者血清PTA低于非感染纽患者(户咐(01). 差异有统计学意义:感染组患 者死亡率(72.7%) 高于非感染级患者死亡率(23.910) ， 羔异有统计学意义俨 0.001);1重现肝炎死亡级患者严重感染牟(78.4%)、 肺部感染-*(49.1%)高于存活组患者(P值分别为0.001 、 0.002) ，死亡生且患者血白细胞数高于存活纽患者，差异有统计学意义 (p 0.(01) 。结论严丁在感染加雯雯~肝炎患者肝功能才遇害，增加其病死伞。在临床上妥合理使用抗蔼索，加强各种感染的防 拢，以改善爱型肝炎怠*1道后，提高其抢救成功率与治愈率。 [关键词 l随性;重型肝炎:感染;预后 doì: 1O.3969/j.issn.1673-5552.201 0.19.0003 {中图分类号}民575.1 【 3汇款标识码)A I 文章编号] 1673叩5552(201创19…侧5-02 Relatior毗úp 缸1aI.y幽恼阳棚1 脚i创却恤f悦目m 缸ld progn唰s in patients with 而ronic severe 剖ral hepatitis ZHANG Yu …feng. ZHU Xíang , MO Zh卜shuo. DePartment of infectíous dísease. 3rd affiliated Hospítal 01 Sun Yat-sen University , Guangzhou 510630. Ghina (Abstract) ot唱ective To investigate the a路。siation between serious infection and prognosis in pati四ts with chrolÚc 白evere viral hepatitis. Metl刷出自 101 Hωpitalized patients with chronic severe 悦ral hepatitis were studied retrosp四tivelyand dividOO into infectOO and non-infecωd groups by the existence of serious infection , as well as the survival and d阅th groups by different prognosis. Liver and kidney function , prothrombin time activity , blood routine and mortality were comparOO betw优n the infectOO and non-infl优tOO group while infection rate and white blood cells compared 协tween the survival and death groups. Rωults， The plasma levels of total bilirubin and creatinine in pat阳市 with seve