枸缘酸钠(国外英文资料).docVIP

枸缘酸钠(国外英文资料) Citrate salt Citrate is mainly used for the determination of hemostasis and hematology. Because of its small toxicity, it is also used in transfusion maintenance fluid. Its anticoagulant mechanism is a soluble chelate that is formed by calcium ions in the citrate and blood to prevent the blood from solidifying and its reaction is Na3C6H5O7 + Ca2 +. Its salt is mainly sodium salt. Its got Na3C6H5O7ZH. The crystals of 5O and 2Na3C6H5O7 + 1H2O2, which are normally used to make 0.129 mol/L (3.8%) or 0.109 mol/L (3.2%) of the blood solution, and the blood press 1:9. For monitoring the oral warfarin anticoagulant therapy in patients, such as citric acid used in the determination of PT, APTT, edge acid sodium concentration (3.2% or 3.8%) should not be changed, because may affect the international standardization ratio (INR). General use of citric acid concentration is 0.129 mol/L sodium than in 0.109 mol/L concentration had higher values of INP, in addition to different sources of clotting enzyme reagent, patients with the same person or plasma coagulation time can vary considerably. So each laboratory used by the source of the blood clotting enzyme reagent live should be as constant as possible, make operation method should be standardized, otherwise it will make to extend or shorten the time for solidification, or make the normal no regularity. The conditional laboratory can use buffer anticoagulant, which is more suitable for the specimen after it is frozen. The effect of a buffer is to maintain the constant pH value of the plasma and prevent the loss of volatile factors. [ The type of anticoagulant Such as natural anticoagulants (heparin, hirudin, etc.) Ca2 + the glue (sodium citrate, potassium fluoride) Principle: the coagulase cant be activated, Ca2 + is coagulant IV, and the rest is protein There are many kinds of anticoagulants and different properties, and they must be selected according to the proper choice of the inspection to obtain the desired re