妊娠合并糖尿病患者胰岛素治疗起始孕周与妊娠结局的关系研究.docVIP

妊娠合并糖尿病患者胰岛素治疗起始孕周与妊娠结局的关系研究 　　[摘要] 目的 探究妊娠合并糖尿病患者胰岛素治疗起始孕周与妊娠结局之间的关系。方法 对2013年1月―2015年1月使用胰岛素治疗妊娠合并糖尿病患者350例资料进行回顾性分析，依照使用胰岛素孕周，分为早期组（1组）182例与晚期组（2组）168例。以饮食控制为基础，使用胰岛素治疗，比较治疗前后餐后2 h血糖值与空腹血糖值，生产结局与不良反应发生率。 结果 经治疗之后，两组受试者的血糖值均在标准范围之内，在入院时，两组患者的餐后与空腹血糖差异无统计学意义（P0.05），且在分娩之前，患者两种血糖水平均比入院时高（P0.05）。 结论 对于妊娠合并糖尿病者，以常规饮食控制为基础，在孕早期使用短效胰岛素加以治疗，可取得满意效果，全面改善妊娠结局，值得进一步推广 [关键词] 胰岛素治疗；妊娠糖尿病；妊娠结局 [中图分类号] R59 [文献标识码] A [文章编号] 1672-4062（2016）10（b）-0003-03 [Abstract] Objective To research the relationship between the initiative pregnant week and pregnant outcome of insulin treatment for patients with pregnancy and diabetes. Methods The data of 350 cases of patients with pregnancy and diabetes treated with insulin from January 2013 to January 2015 were retrospectively analyzed， and the patients were divided into the group 1 with 182 cases and group 2 with 168 cases according to the pregnant week， and the insulin was used for treatment based on the dieting control， and the 2-hour？postprandial blood sugar， fasting blood sugar， birth outcome and incidence rate of adverse reactions were compared before and after treatment. Results After treatment， the blood sugar value of the two groups was within the standardized range， on admission， there was no obvious difference in the postprandial and fasting blood sugar between the two groups（P0.05）， before delivery， the two blood sugar levels of patients were higher than those on admission（P0.05）. Conclusion For patients with pregnancy and diabetes， the use of short-acting？insulin for treatment in the early pregnancy period can obtain a satisfactory effect and can comprehensively improve the pregnant outcome， which is worth further promotion. [Key words] Insulin treatment； Gestational diabetes； Pregnancy outcome 和过去相比，我国医疗水平得到大幅度提升，妊娠女性也更加注重自身保养，一旦出现异常会在第一时间就诊。但值得注意的是，由于饮食过于精良，导致妊娠期糖尿病的发生概率也呈现出逐年上升的趋势，我国各大医疗机构也致力于寻找治疗这种疾病的有效方式[1]。所谓妊娠期糖尿病，主要指的是女性怀孕期间首次出现差异化糖耐量上升情况，有统计指出[2]，该疾病的发生率约为6%～7%。如患者未在第一时间接受到合理治疗，则很容易出现巨大儿，难产，畸形胎的发生率。迄今为止，胰岛素