响应面优化减压内部沸腾法提取辣椒碱工艺.pdfVIP

72 2013, Vo1.34, No. lO 国自翻军 ※王艺技术 响应面优化减压内部沸腾法提取辣椒碱王艺 柳昌武，陈晓光，韦藤幼飞童张法 (广西大学化学化工学院，广西石化资源加工及过程强化技术重点实验室，广西南宁 530004) 摘 要z 优化辣椒碱的减压内部沸腾法提取工艺，以提高收率和产品质量。首先采用析因设计确定需要优化的影响 较大因素，然后通过最陡爬坡试验逼近这些因素的最佳区域，最后使用响应面对这些因素进行优化并与传统的醇 提工艺进行对比。结果显示:影响较大的因素有解吸剂乙醇体积分数和用量以及提取剂乙醇体积分数:当这3个因 素的量分别为829毛、 3.5mL饱和44%时，在50C 条件下提取5min辣椒碱的提取得率为0.211%: 与传统乙醇回流法相 比，虽然提取得率仅提高0.011% ，但提取液的质量明显提高，把两者的提取液过柱纯化，减压内部沸腾提取液的辣 椒碱收率及纯度分别比回流法提高15.8%和5.0%。减压内部沸腾法不但缩短了提取时间，而且提取液质量高，具有 良好的工业化前景。 关键词:辣椒碱:响应面优化:减压内部沸腾:提取 Response Surface Methodology for Optimization of Capsaicin Extraction by Vacuum Innner Ebullition LIU Chang-wu , CHEN Xiao-guang , WEI Teng-you* , TONG Zhang-fa (Guangxi Key Laboratory of Chemica1 Resource Processing and Process Intensification Technology , School of Chemistry and Chemical Engineering , Guangxi University , Nanning 530004, China) Abstract: The extraction of capsaicin by vacuum inner ebullition was optimized to obtain improved yield and quality. Firstly , factori a1 design analysis was used to identify main optimization parameters. Secondly, their optimal region was approached by the steepest ascent method. Finally , response surface methodology was employed to optimize the parameters and the optimized process was compared with traditional ethanol extraction. Ethanol concentration and dosage for capsaicin adsorption and ehanol concentration for caps缸cin desorption were identified as main variables. The extraction efficiency of capsaicin was 0.211 % under the conditions of extraction at 50 C for 5 min with 829毛 ethanol at a solvent-to-solid ratio of 3.5 mUg and desorption with 44% ethanol. Compared with traditiona1 ethanol extraction, the quality of the extract obtain