综合治疗原发性肝癌的临床观察.pdfVIP

海军总医院学报2008年3月第21卷第1期 1 综合治疗原发性肝癌的I晦床观察 康静波，聂 青，张丽萍，王仁秋，李启亮 (海军总医院放疗科，北京 100037) 摘要：目的 分析伽玛刀配合热疗治疗原发性肝癌的效果。方法 自2004年4月～2005年 8月，原发 性肝癌患者65例行单纯伽玛刀治疗，3l例给予伽玛刀治疗配合热疗。结果 治疗后3个月总的有效率为 83，3 (80／96)。单纯伽玛刀组的1年、2年局部控制率分别为 61．5 (40／65)、35，4 (23／65)，1年、2年生 存率分别为63，1 、32，3 ；伽玛刀配合热疗组的1年、2年局部控制率分别为64．5 (2o／31)、35．5 (11／ 31)，1年、2年生存率分别为67，7 ，38．7 。随访期内未见严重放射性并发症。结论 对原发性肝癌采用 伽玛刀配合热疗是较有效的局部治疗方式。 ． 关键词：原发性肝癌；伽玛刀；温热疗法 中图分类号：R735．7 文献标识码：B 文章编号：1009—3427(2008)01-000卜O3 Clinical Study of the Combined Therapy of Y—Knife with Hyperthermla for Primary Hepatoceilular Carcinoma KANG Jing—bo，NIE Qing，ZHANG Li-ping，WANG Ren—qiu，L Qi—liang (Department of Radiation Oncology，Naval General Hospital，Beijing 100037，China) Abstract：Objective To investigate the clinical effect of 7-knife Combined with hyper— thermia for Primary H patocellular Carcinoma．Methods From April 2004 to August 2005， 65 patients with primary hepatocellular carcinoma were treated by 一knife alone，31 patients with primary hepatocellular carcinoma were treated by 一knife combined with hyperthermia． Results Three months after treatment，the overall response rate was 83．30 (80／96)．The local control rates at 1 and 2 years were 61．5％(40／65)and 35．4 (23／65)，the survival rates at 1 and 2 years were 63．1 and 32．3 respectively in 7-knife alone group．The local control rates at 1 and 2 years were 64．5％(20／31)and 35．5 (11／31)，the survival rates at 1 and 2 years were 6 7．7 and 38．7％，respectively in 7-knife combined with hyperthermia．No serious complications were found in the follow up period．Conclusion 一knife combined with hyperthermia is an effective treatm