高压氧治疗脑梗死后抑郁的疗效观察.pdfVIP

医学临床研究 2007年12月 第24卷 第12期 J Clin Res，Dec．2007，Vol 24，№12 · 论著· 高压氧治疗脑梗死后抑郁的疗效观察 严秋凤 徐燕 谭佩珍 刘秋庭 周爱华 周妮娜 杨倩 (湖南省第二人民医院神经内二科，湖南 长沙 410007) [摘要]【目的】观察高压氧(HBO)治疗对脑梗死后抑郁(PID)及神经功能康复的影响。【方法】将80例PID 患者随机分为治疗组和对照组，在常规治疗基础上，治疗组加用Ht30，每日1次，每次120 min，观察两组治疗 前、后汉密顿抑郁量表(HAMD)评分，中国卒中量表(CSS)和日常生活活动能力(ADL)评分变化。【结果】一个 月后治疗组HAMD评分，cSs评分及ADL评分均较治疗前和对照组同期有明显改善(P0 01)，而对照组无 明显变化(PO．05)。【结论]HBO可明显改善脑梗死后押郁程度并能促进神经功能康复。 [关键词] 高压氧； 脑梗塞／治疗； 脑梗塞／并发症； 抑郁症／治疗； 抑郁症／病因学 Efficacy of Hyperbaric Oxygen for the Treatment of Post··cerebral—-infarction Depression YAN Qiu—feng， XU Yah， TAN Pei—zheng，et al(Department of Neurology，the Second People 5 Hospital 0厂Hunan Province，Changsha 410007，China) ~Abstract][Objective]To observe the effects of hyperbaric oxygen(HBO)in the treatment of post—cerebral—in— farction depression(PID)and neurological functional rehabilitation．[Methods]Eighty patients with PID were ran— domly divided into two groups．treatment group and control group．Patients in the treatment group were given Ht30 treatment in addition to the regular treatment，0．d．for 120 minutes．Changes of scores of Hamilton depression rating scale(HAMD)，Chinese stroke scale(CSS)and activities of daily living(ADL)before and after treatment in two groups were observed．[Results]After one month。treatment scores of HAMD，CSS and ADL in the treatment group had obviously better results than those before treatment and the control group(P0．O1)。while scores in the control group had no significant difference(P0．05)．[Conclusion]HBO may improve the depressive symptom and neurological function rehabilitation in P1D patients． [Key words] hyperbaric oxygenation； brain infarction／TH； brain infarction／CO； depressive disor— der／TH； depressive disorder／ET [中图分类号] R743．33 [文献标识码] A [文章编号] 1671—7171(2007)12—2l15—02 脑梗死患者除有各种躯体症状外，常伴有情感 脑血管病会议制订的脑梗死诊断标准 ]，经头部CT 障碍，其中以抑郁最多见。脑