semen quality of 16 835 infertile men in china - 中南大学学报（医学版）.pdf

中南大学学报（医学版） 2014, 39(2) ; J Cent South Univ (Med Sci) 157 DOI:10.11817/j.issn.1672-7347.2014.02.008 /xbwk/fileup/PDF/201402157.pdf 16 835例中国不育男性的精液质量分析 1,2 1 2 1 李维娜 ，朱文兵，唐章明，刘刚 (1. 中南大学生殖与干细胞工程研究所；2. 中信湘雅生殖与遗传专科医院，长沙 410078) [摘要]目的：通过精液常规检查评价大样本量的不育男性的生育能力，为男性不育症的临床治疗和疗效观察提供 科学依据。方法：收集16 835例不育男性的精液标本，以1 567例精子库候选供精者精液标本作为普通人群对照组，采 用计算机辅助精液分析技术(computer assisted sperm analysis ，CASA )进行精液常规检测并对结果进行统计学分析。结 果：不育患者精液异常主要表现为弱精症。不育组无精症、弱精症、少弱精症患者比例高于对照组，不育组少精症 患者比例低于对照组(P 0.001)。结论：弱精症、无精症、少弱精症与不育相关，而单纯少精症不一定与不育相关。 [关键词] 不育；弱精症；少精症；无精症；少弱精症 Semen quality of 16 835 infertile men in China 1,2 1 2 1 LI Weina , ZHU Wenbing , TANG Zhangming , LIU Gang (1. Institute of Human Reproduction and Stem Cell Engineering, Central South University, 2. Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410078, China) ABSTRACT Objective: To evaluate the fertility of infertile males of large samples by the routine semen examination, and to provide a scientific basis for clinical treatment of male infertility and improve efficacy. Methods: We collected 16 835 semen specimens of infertile man in our hospital (the infertility group), and 1 567 semen specimens of sperm donating candidates from the sperm bank of our hospital (the control group). Semen routine examination was performed by computer-assisted