中药抗肾纤维化的研究进展.pdfVIP

医学综述2008年7月第14卷第13期 Medical Recapitulate，Jul 2008．V01．14．No．13 中药抗肾纤维化的研究进展 曹树琦 ，傅晓骏 (1．浙江中医药大学，杭州 310053；2．浙江中医药大学附属金华中医院肾内科，浙江金华321017) 中图分类号：R692．6 文献标识码：A 文章编号：1006-2084(2008)13~051-04 摘要：肾纤维化是各种慢性肾脏疾病进展到终末期肾衰竭的共同通路。近年来，对单味中药及 尿毒症的最早应用，直至 其有效提取物、中药复方在抗肾纤维化研究方面取得了一定成果，体现了中医药抗肾纤维化的优势。 1984年才开始逐渐有冬虫 随着现代科学研究手段的不断进步，特别是对中药复方临床研究的进一步深入，有望从中药复方中 开发出具有抗肾纤维化的新型药物应用于临床。现就中药抗肾纤维化的研究进展进行综述。 夏草治疗慢性肾衰竭的病例 关键词：肾纤维化；中药；单味药；复方 · 总结报道，并开始了人工虫 Progresses in Study on Traditional Chinese Medicine against Renal Fibrosis CAO Shu—qi ．F￡，Xiao— 草菌丝的临床及药理研究。 jun ．(1．Zhefiang Traditional ChineseMedicalUniversity；Hangzhou 310053，China；2．Department ofNeph— 目前，虫草制剂在临床 rology；Affiliated Jinhua TCM Hospital ofZhejiang Traditional Chinese Medical Univers讧y Zhejiang Jinhua 321017．c^ina) 上应用十分普遍，其疗效已 Abstract：Renal fibrosis is iS the common pathway for a variety of chronic lenal disease to final stage re— hal failure．Recently，much progress were made in study on single medicinal herbs and its extract，compound 经得到大部分临床医师和患 medicinal herbs against．which gave the advantages of traditional Chinese medicine against Renal Fibrosis． 者的认可。程晓霞等_2I3 对 W tlle development of modem research metllod．especially tlle deeped clinical research on compound me— dicinal herbs．new types of medicine will be exploited from compound medicinal herbs to use in clinic experi— 210例慢性肾小管间质病变 ence against leaal fibrosis in future．This article reviewed the development of traditional Chinese medicine a— gainst renal fibrosis． 患者应用百令胶囊治疗，结 Key words：Renal fibrosis； ditional Chinese Medicine：Single medicinal herbs；Compound medici— 果在改善肌酐清除率、