直肠癌术后咀嚼口香糖促进胃肠康复随机对照探究.docVIP

直肠癌术后咀嚼口香糖促进胃肠康复随机对照探究摘要：目的 探讨直肠癌术后咀嚼口香糖促进胃肠功能恢复的有效性。方法 前瞻性纳入2010年1月至2010年7月行择期直肠癌手术的患者160例，并随机分为实验组（n=80）和对照组（n=80）。实验组术后咀嚼口香糖，对照组术后不咀嚼口香糖。盲法采集术后胃肠功能恢复情况和胃肠道并发症指标，并比较两组间的差异。结果 本研究实际纳入病例155例，实验组78例，对照组77例，两组患者基本情况一致。所有纳入患者均能良好耐受术后咀嚼口香糖。实验组术后首次闻及肠鸣音时间（P＝0.036），首次排气时间、首次排便时间和术后住院时间明显短于对照组（P0.省略 [Abstract]Objective: To determine the effectiveness of chewing gum in promoting postoperative bowel recovery for patients with rectal cancer. Methods: Prospectively enrolled 160 patients underwent elective rectal cancer from January 2010 to July 2010, were randomly assigned into two groups. The patients in experimental group (n=80) were given gum for chewing postoperatively, while nothing was offered to control group (n=80). The outcomes were blindly assessed and compared between two groups, including postoperative bowel function recovery situation and complications. Results: 155 patients underwent rectal cancer were enrolled in experimental group (n=78) and control group (n=77). The baselines characteristics of two groups were statistically similar. All the patients tolerated chewing gum well. The postoperative intestinal sounds first heard was significantly shorter in experimental group as compared to control group (P=0.036), as well as passage of first flatus, first bowel movement and length of postoperative hospital stay(p0.05). Conclusion: Chewing gum for patients with rectal cancer could enhance the postoperative bowel function recovery, relieve gastrointestinal discomfort, shorten the hospital stay, and finally improve the postoperative quality of life. Key words：Rectal Cancer; Chewing Gum; Bowel Recovery; Randomized Controlled Trial 中图分类号：R73 文献标识码：B 文章编号：1004-7484（2011）18-0057-04 术后肠梗阻是直肠癌术后的常见并发症之一，研究显示其发生率为26%～31%[1]。术后胃肠功能的延迟恢复会导致腹胀、恶心、呕吐等不适，降低患者的术后生活质量，延长术后住院日。而且由于直肠癌手术的特殊性，医生从安全的角度考虑倾向于延长患者术后的禁食时间，减少吻合口瘘发生的风险，阻碍了患者的术后胃肠功能康复。本研究利用“假饲”原理，采用随机对照试验探讨直肠癌术后咀嚼口香糖促进胃肠功能恢复的有效性。 1 资料与方法 1.1 临床资料 本研究拟前瞻性纳入2010年1月～2010年7月期间于我院住院行择期直肠癌手术患者160例。排除标准：①急诊入院行剖腹探查