腹膜透析在重症急性胰腺炎救治中应用研究.docVIP

腹膜透析在重症急性胰腺炎救治中应用研究【摘要】目的 探讨腹膜透析在重症急性胰腺炎救治中应用。 方法 采取腹膜透析治疗组46例，采取基础治疗对照组40例，观察两组患者的血淀粉酶恢复正常时间、死亡率等情况，并进行比较。 结果 腹膜透析治疗组46例中死亡5例，死亡率10.86%，基础治疗对照组40例中死亡12例，死亡率达30.00%；经统计学分析比较，差异有统计学意义( P 0.05)。 结论 膜腹透析在重症急性胰腺炎救治中应用可以有效的对循环中炎症介质进行清除，减轻全身炎症反应；可以将渗入腹腔的胰酶、炎症介质进行清除减少对胰腺及周围器官破坏；可以减轻胰腺水肿、促进肠麻痹恢复。 【关键词】 膜膜透析；重症急性胰腺炎；应用分析 Application analysis of peritoneal dialysis in severe acute pancreatitis treatment YANG Fei-yun. First Affiliated Hospital of Xinxiang Medical College,Xinyang 453100,China  【Abstract】 Objective To explore the peritoneal dialysis in severe acute pancreatitis treatment application. Methods To take on is divided into 46 cases of peritoneal dialysis treatment group to take the basic treatment in the control group of 40 cases, two groups were observed serum amylase normal time, mortality, and compare. Results 46 cases of peritoneal dialysis treatment group, 5 patients died, a mortality rate of 10.86% basic treatment control group, 40 cases of death in 12 cases, the mortality rate of 30.00%.Signficant difference between the two group( P 0.05). Conclusion Abdominal dialysis membrane in severe acute pancreatitis treatment can be effective mediators of inflammation in the loop to clear,reduce the systemic inflammatory response; can penetrate the abdominal cavity of trypsin, inflammatory mediators to be cleared to reduce the destruction of the pancreas and surrounding organs,reduce pancreatic edema, and promote the recovery of intestinal paralysis. 【Key words】 Membrane membrane dialysis; Severe acute pancreatitis; Application analysis 腹膜透析是临床上较为常见的、应用广泛，主要针对肾脏疾病、危重症患者急救措施；重症急性胰腺炎(SAP)是由于多种因素导致胰腺弥漫性出血和组织坏死的急腹症,由于本病发展迅速，可以导致严重的炎症连锁反应，诱发出现多器官功能衰竭,死亡病例达到30%～50%［1］。在对重症急性胰腺炎救治过程中，清楚各种炎症介质减轻和阻断炎症因子连锁反应，减轻临床症状，促进疾病康复重要措施，应用腹膜透析对重症急性胰腺炎进行救治，取得较为理想的效果，报告如下。 1 资料与方法 作者单位：453100 卫辉，新乡医学院第一附属医院 1.1 入选标准 所以病例诊断依据中华医学会胰腺外科学组制度的重症急性胰腺炎诊断标准［2］：有明显的诱因，表现为急性腹膜炎、腹部压痛、反跳痛，肠道中毒性麻痹，伴或不伴循环障碍，表现为低血压，严重者可以导致休克，腹部穿刺出血性腹水；经腹部超声及CT等影像学检查胰腺肿胀，腹腔局部积液。 1.2 临床资料