国产室间隔缺损封堵器与Amplatzer封堵器的疗效比较.pdfVIP

· 68· 心脏杂志 (Chin Heart J)2008，20(1) · 临床研究· 国产室间隔缺损封堵器与Amplatzer封堵器的疗效比较 王 威，曾国洪，张智伟，李渝芬，石继军，李俊杰，谢育梅 (广东省人民医院心儿科，广东广州510100) 摘要：目的 比较国产室间隔缺损封堵器与Amplatzer封堵器在经导管室间隔缺损封堵术中的疗效。方法 41例患 儿采用Amplatzer封堵器，76例患儿采用国产封堵器进行室间隔缺损封堵术，对比两组的疗效、并发症和费用等情况。 结果 国产组75例封堵成功(成功率99％)，进口组40例封堵成功(成功率98％)。两组患儿术前各项临床指标、手 术和x线曝光时间、封堵成功率及住院天数，术后各项并发症发生率比较差异无统计学意义，两组患儿治疗前后左室 舒张末径、收缩末径及C／T值减少程度无明显差异，治疗总费用进口组明显高于国产组。结论 国产室间隔缺损封 堵器与Amplatzer封堵器相比较其疗效、并发症发生率无显著差异，治疗费用低，临床应用前景广泛。 关键词：室间隔缺损 ；介入治疗；对比研究 中图分类号：R541．1 文献标识码：A 文章编号：1009-7236【2008)ol-068-03 Transcatheter closure of ventricular septal defect：Comparison of Amp- latzer septal occluder and a China-made septal occluder WANG Wei，ZENG Guo一 ， ，ZHANG Zhi—wei，L1 Yufen，SH1 Jijun，LI Jun-jie，X1E Yu—mei (Department of Pediatrics，Guangdong Cardiovascular Institute，Guangdong Provincial people S hospital， Guangzhou 510100，Guangdong，China) Abstract：AIM To compare the efficiency of transcatheter closure of ventricular septal defect by using Amplatzer septal occluder and a new septal occluder made in China．METHODS Forty—one patients were treated with Amplatzer septal occluder and 76 patients were treated with a China·-made septal oeelu·· der during the same period．The efficiency，complications and cost of both groups were compared． RESULTS No significant difference was found in comparing the preoperatively clinical indexes，opera— tive and exposure time，hospital days and the rate of complete closure and complication．No significant difference was found in the decrease of left ventricular systolic and diastolic end，as well as C／T．The to． tal cost of the Amplatzer septal occluder group was much higher than that of the China··made septal occlu·· der group．CONCLUSION There is no significant difference in the rate of com